摘要
背景：HE4可能是妇科癌症复发的有价值的早期指标。 许多研究表明血清HE4的高表达水平与卵巢和子宫内膜癌复发相关。 高HE4水平可能是预测这些癌症预后不良的独立因素。 目的：本研究回顾了血清HE4水平与卵巢癌和子宫内膜癌复发之间的关系。 结论：HE4通过促进癌细胞从G1期跳至S期，维持细胞活力，促进细胞增殖，抑制细胞凋亡，增加药物治疗抗性，显示恶性行为。 需要进一步的研究来验证血清HE4水平升高与卵巢癌和子宫内膜癌的复发相关。
关键词: HE4，妇科癌症，卵巢癌，子宫内膜癌，癌症复发，预后。
图形摘要
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