Abstract
A great deal has been learned about the behaviour of monoamine oxidase in the 75 years since it was first discovered, but there is still a great deal left to understand. This review concentrates on the dynamic aspects of our knowledge of the interactions of MAO with substrates and inhibitors and how it may collaborate with other enzymes, with particular emphasis on aspects that remain to be clarified.
Keywords: monoamine oxidases, substrates, inhibitors
Current Medicinal Chemistry
Title: Monoamine Oxidases: Certainties and Uncertainties
Volume: 11 Issue: 15
Author(s): Keith F. Tipton, Sinead Boyce, Jeff O'Sullivan, Gavin P. Davey and Joe Healy
Affiliation:
Keywords: monoamine oxidases, substrates, inhibitors
Abstract: A great deal has been learned about the behaviour of monoamine oxidase in the 75 years since it was first discovered, but there is still a great deal left to understand. This review concentrates on the dynamic aspects of our knowledge of the interactions of MAO with substrates and inhibitors and how it may collaborate with other enzymes, with particular emphasis on aspects that remain to be clarified.
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Cite this article as:
Tipton F. Keith, Boyce Sinead, O'Sullivan Jeff, Davey P. Gavin and Healy Joe, Monoamine Oxidases: Certainties and Uncertainties, Current Medicinal Chemistry 2004; 11 (15) . https://dx.doi.org/10.2174/0929867043364810
DOI https://dx.doi.org/10.2174/0929867043364810 |
Print ISSN 0929-8673 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-533X |
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