Abstract
A great deal has been learned about the behaviour of monoamine oxidase in the 75 years since it was first discovered, but there is still a great deal left to understand. This review concentrates on the dynamic aspects of our knowledge of the interactions of MAO with substrates and inhibitors and how it may collaborate with other enzymes, with particular emphasis on aspects that remain to be clarified.
Keywords: monoamine oxidases, substrates, inhibitors
Current Medicinal Chemistry
Title: Monoamine Oxidases: Certainties and Uncertainties
Volume: 11 Issue: 15
Author(s): Keith F. Tipton, Sinead Boyce, Jeff O'Sullivan, Gavin P. Davey and Joe Healy
Affiliation:
Keywords: monoamine oxidases, substrates, inhibitors
Abstract: A great deal has been learned about the behaviour of monoamine oxidase in the 75 years since it was first discovered, but there is still a great deal left to understand. This review concentrates on the dynamic aspects of our knowledge of the interactions of MAO with substrates and inhibitors and how it may collaborate with other enzymes, with particular emphasis on aspects that remain to be clarified.
Export Options
About this article
Cite this article as:
Tipton F. Keith, Boyce Sinead, O'Sullivan Jeff, Davey P. Gavin and Healy Joe, Monoamine Oxidases: Certainties and Uncertainties, Current Medicinal Chemistry 2004; 11 (15) . https://dx.doi.org/10.2174/0929867043364810
DOI https://dx.doi.org/10.2174/0929867043364810 |
Print ISSN 0929-8673 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-533X |
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
- Announcements
Related Articles
-
Recent Developments in Nano-Drug Delivery Systems Loaded by Phytochemicals for Wound Healing
Mini-Reviews in Medicinal Chemistry Single Nucleotide Polymorphisms in Neonatal Necrotizing Enterocolitis
Current Pediatric Reviews Expression of Heme Oxygenase-1 in Response to Proteasomal Inhibition
Protein & Peptide Letters Dry Age-Related Macular Degeneration: Recent Progress of Therapeutic approaches
Current Molecular Pharmacology Phenazine 5,10-Dioxide Derivatives as Hypoxic Selective Cytotoxins: Part II. Structure-Activity Relationship Studies
Medicinal Chemistry Magainin 2-PGLa Interactions in Membranes - Two Peptides that Exhibit Synergistic Enhancement of Antimicrobial Activity
Current Topics in Medicinal Chemistry Chitosan Formulations as Carriers for Therapeutic Proteins
Current Drug Discovery Technologies Inflammaging of Female Reproductive System: A Molecular Landscape
Current Aging Science Processing and Utilization of Palm Date Fruits for Edible Applications
Recent Patents on Food, Nutrition & Agriculture Green Tea Catechins and Cardiovascular Health: An Update
Current Medicinal Chemistry A Comprehensive Review of <i>Garcinia pedunculata Roxb</i>. and its Therapeutic Potential
Mini-Reviews in Medicinal Chemistry Pharmacological Manipulation of Neural Progenitor Pathways In Situ: Possibilities for Neural Restoration in the Injured Adult Brain
Current Medicinal Chemistry - Central Nervous System Agents Editorial (Thematic Issue: Roles of Sumoylation and Phosphorylation in Normal Physiology and Human Diseases)
Current Molecular Medicine Triglyceride Level Affecting Shared Susceptibility Genes in Metabolic Syndrome and Coronary Artery Disease
Current Medicinal Chemistry Emerging Therapies Targeting Tumor Vasculature in Multiple Myeloma and other Hematologic and Solid Malignancies
Current Cancer Drug Targets Hybrid SPECT/CT Imaging in Neurology
Current Radiopharmaceuticals Pharmaceutical Strategies Enhancing Cell Penetration Efficiencies of Non-Viral Gene Delivery Systems
Current Gene Therapy Inspiratory and Expiratory Chest High-resolution CT: Small-airway Disease Evaluation in Patients with COVID-19
Current Medical Imaging A Review of Recent Patents on the Protozoan Parasite HSP90 as a Drug Target
Recent Patents on Biotechnology Pyrrolo[2,3-d]Pyrimidines as Kinase Inhibitors
Current Medicinal Chemistry