[1]
Poloznikov, A.; Gazaryan, I.; Shkurnikov, M.; Nikulin, S.; Drapkina, O.; Baranova, A.; Tonevitsky, A. In vitro and in silico liver models: current trends, challenges and opportunities. ALTEX, 2018, 35, 397-412.
[2]
Smirnova, N.A.; Rakhman, I.; Moroz, N.; Basso, M.; Payappilly, J.; Kazakov, S.; Hernandez-Guzman, F.; Gaisina, I.N.; Kozikowski, A.P.; Ratan, R.R.; Gazaryan, I.G. Utilization of an in vivo reporter for high throughput identification of branched small molecule regulators of hypoxic adaptation. Chem. Biol., 2010, 17, 380-391.
[3]
Neitemeier, S.; Dolga, A.M.; Honrath, B.; Karuppagounder, S.S.; Alim, I.; Ratan, R.R.; Culmsee, C. Inhibition of HIF-Prolyl-4-hydroxylases prevents mitochondrial impairment and cell death in a model of neuronal oxytosis. Cell Death Dis., 2016, 7, e2214.
[4]
Karuppagounder, S.S.; Alim, I.; Khim, S.J.; Bourassa, M.W.; Sleiman, S.F.; John, R.; Thinnes, C.C.; Yeh, T-L.; Demetriades, M.; Neitemeier, S.; Cruz, D.; Gazaryan, I.; Killilea, D.W.; Morgenstern, L.; Xi, G.; Keep, R.F.; Schallert, T.; Tappero, R.V.; Zhong, J.; Cho, S.; Maxfield, F.R.; Holman, T.R.; Culmsee, C.; Fong, G-H.; Su, Y.; Ming, G.; Song, H.; Cave, J.W.; Schofield, C.J.; Colbourne, F.; Coppola, G.; Ratan, R.R. Therapeutic targeting of oxygen-sensing prolyl hydroxylases abrogates ATF4-Dependent neuronal death and improves outcomes after brain hemorrhage in several rodent models. Sci. Transl. Med., 2016, 8, 328ra29.
[5]
Poloznikov, A.A.; Zakhariants, A.A.; Nikulin, S.V.; Smirnova, N.A.; Hushpulian, D.M.; Gaisina, I.N.; Tonevitsky, A.G.; Tishkov, V.I.; Gazaryan, I.G. Structure-activity relationship for branched oxyquinoline HIF activators: effect of modifications to phenylacetamide “Tail”. Biochimie, 2017, 133, 74-79.
[6]
Osipyants, A.I.; Smirnova, N.A.; Khristichenko, A.Y.; Hushpulian, D.M.; Nikulin, S.V.; Chubar, T.A.; Zakhariants, A.A.; Tishkov, V.I.; Gazaryan, I.G.; Poloznikov, A.A. Enzyme-substrate reporters for evaluation of substrate specificity of HIF prolyl hydroxylase isoforms. Biochem., 2017, 82, 1207-1214.
[7]
Aleksandrova, A.V.; Burmistrova, O.A.; Fomicheva, K.A.; Sakharov, D.A. Maintenance of high cytochrome P450 expression in HepaRG cell spheroids in DMSO-Free medium. Bull. Exp. Biol. Med., 2016, 161, 120-124.
[8]
Zakhariants, A.A.; Burmistrova, O.A.; Shkurnikov, M.Y.; Poloznikov, A.A.; Sakharov, D.A. Development of a specific substrate-inhibitor panel (Liver-on-a-Chip) for evaluation of cytochrome P450 activity. Bull. Exp. Biol. Med., 2016, 162, 170-174.
[9]
Zakharyants, A.A.; Burmistrova, O.A.; Poloznikov, A.A. The use of human liver cell model and cytochrome p450 substrate-inhibitor panel for studies of dasatinib and warfarin interactions. Bull. Exp. Biol. Med., 2017, 162, 515-519.
[10]
Semenova, O.V.; Petrov, V.A.; Gerasimenko, T.N.; Aleksandrova, A.V.; Burmistrova, O.A.; Khutornenko, A.A.; Osipyants, A.I.; Poloznikov, A.A.; Sakharov, D.A. Effect of circulation parameters on functional status of HepaRG spheroids cultured in microbioreactor. Bull. Exp. Biol. Med., 2016, 161, 425-429.
[11]
Shirasaka, Y.; Sager, J.E.; Lutz, J.D.; Davis, C.; Isoherranen, N. Inhibition of CYP2C19 and CYP3A4 by omeprazole metabolites and their contribution to drug-drug interactions. Drug Metab. Dispos., 2013, 41, 1414-1424.
[12]
Hedrich, W.D.; Hassan, H.E.; Wang, H. Insights into CYP2B6-mediated drug-drug interactions. Acta Pharm. Sin. B, 2016, 6, 413-425.
[13]
Zanger, U.M.; Klein, K. Pharmacogenetics of cytochrome P450 2B6 (CYP2B6): Advances on polymorphisms, mechanisms, and clinical relevance. Front. Genet., 2013, 4, 24.
[14]
Kharasch, E.D.; Regina, K.J.; Blood, J.; Friedel, C. Methadone pharmacogenetics. Anesthesiology, 2015, 123, 1142-1153.