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Current Analytical Chemistry

Editor-in-Chief

ISSN (Print): 1573-4110
ISSN (Online): 1875-6727

Derivatization Coupled to Chemiluminescence Detection

Author(s): George Z. Tsogas, Dimosthenis L. Giokas and Athanasios G. Vlessidis

Volume 10, Issue 3, 2014

Page: [305 - 319] Pages: 15

DOI: 10.2174/1573411010999131219101823

Price: $65

Abstract

In this work, an overview of analytical methods employing derivatization reactions in chemiluminescence detection is presented. Method development, instrumental configurations and hyphenated manifolds, specifically designed or implemented to accommodate CL detection, along with their analytical applications for the determination of a wide variety of organic compounds such as biochemically active substances, pharmaceutical active compounds, environmental pollutants and food constituents, are summarized. The analytical merits of derivatization reactions in chemiluminescence analysis and their potential for the development of sensitive and selective methods are elucidated.

Keywords: Chemiluminescence, derivatization, liquid chromatography, capillary electrophoresis.

Graphical Abstract


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