癌症治疗的新传递工具---细胞外囊泡

Title:Extracellular Vesicles as Novel Delivery Tools for Cancer Treatment

Volume: 16 Issue: 1

Author(s): Erdogan Pekcan Erkan and Okay Saydam

Affiliation:

关键词: 癌症，传递，细胞外囊泡，治疗学

摘要: Extracellular vesicles (EVs) are different types of membrane-derived vesicles that originate from the endosomal pathway or the plasma membrane. These vesicles are used as "carriers" in intercellular communication, and are responsible for the transfer of biological cargo (lipids, proteins, RNA species, and DNA) between different cells. Despite the shortcomings in our knowledge of EV biology, attempts to employ EVs as natural delivery tools for therapeutic purposes have been partly successful in different settings. In this review, we highlight this unique potential of EVs, and discuss previous examples and future scenarios.

Cite this article as:

Erdogan Pekcan Erkan and Okay Saydam , Extracellular Vesicles as Novel Delivery Tools for Cancer Treatment, Current Cancer Drug Targets 2016; 16 (1) . https://dx.doi.org/10.2174/1568009615666150923115439