A Convenient Synthesis of 2-Imino-1,3-Thiazine-4-One Derivatives from the Reaction of Primary Amines and Phenyl Isothiocyanate in the Presence of Acryloyl Chloride

Title:A Convenient Synthesis of 2-Imino-1,3-Thiazine-4-One Derivatives from the Reaction of Primary Amines and Phenyl Isothiocyanate in the Presence of Acryloyl Chloride

Volume: 17 Issue: 7

Author(s): Amin Zolali, Farough Nasiri and Sonia Omid-Niakan

Affiliation:

Keywords: 1, 3-Thiazine, dithiocarbamate, MCRs, multicomponent, one-pot.

Abstract: An efficient, one-pot and three-component synthesis of biologically important heterocyclic compounds is described from the reaction of primary amines and phenyl isothiocyanate in the presence of acryloyl chloride at room temperature without the need to use any catalyst.

Cite this article as:

Zolali Amin, Nasiri Farough and Omid-Niakan Sonia, A Convenient Synthesis of 2-Imino-1,3-Thiazine-4-One Derivatives from the Reaction of Primary Amines and Phenyl Isothiocyanate in the Presence of Acryloyl Chloride, Combinatorial Chemistry & High Throughput Screening 2014; 17 (7) . https://dx.doi.org/10.2174/1386207317666140313110334