Antitubercular Drug Development: Current Status and Research Strategies

Title:Antitubercular Drug Development: Current Status and Research Strategies

Volume: 13 Issue: 11

Author(s): Kuldipsinh P. Barot, Stoyanka Nikolova, Illiyan Ivanov and Manjunath D. Ghate

Affiliation:

Keywords: Tuberculosis, molecular targets, novel agents in evaluation phase, novel antitubercular agents, novel heterocyclic molecules.

Abstract: Recent developments and novel research strategies are adopted widely to discover and develop the new drugs to treat tuberculosis. New antitubercular drugs are urgently needed because tuberculosis remains a global health problem as around nine million new cases are estimated each year with almost two million fatalities. It states the impact and outcomes that have made a significant effect in antitubercular drug development. We are presenting current status of tuberculosis, antitubercular drug development, novel molecular targets, novel agents in clinical and pre-clinical development and some efforts that are being made in the development of novel molecules based on different pharmacophores as lead compounds and recent strategies.

Cite this article as:

Barot P. Kuldipsinh, Nikolova Stoyanka, Ivanov Illiyan and Ghate D. Manjunath, Antitubercular Drug Development: Current Status and Research Strategies, Mini-Reviews in Medicinal Chemistry 2013; 13 (11) . https://dx.doi.org/10.2174/13895575113139990076