Amino Acid Pairs Susceptible to Variants in Human Protein C Precursor

Guang      Wu; Shaomin      Yan

doi:10.2174/0929866054395248

Abstract

In this study, we analyze the amino acid pairs in human protein C precursor to determine which amino acid pairs are more susceptible to 71 variants from missense mutant human protein C precursor. The results show 85.92% of 71 variants occur at randomly unpredictable amino acid pairs accounting for 61.96% of amino acid pairs in protein C.

Keywords: protein c, probability, randomness, thrombophilia, variant, cycloamylose

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