摘要
多糖是海藻中丰富的化学成分,其在不同领域如医药、生物医学化妆品和营养物质中应用广泛。对这些化合物的研究兴趣来源于其广泛的生物活性如其抗过敏、神经保护、细胞毒性保护、心血管保护,细胞毒性、抗凝血、抗血栓、降血脂、抗病毒、镇痛、免疫调节,这些活性使得他们成为具有广阔前景的生物制品和生物材料。炎症过程是免疫系统介导的复杂的事件,达到保护宿主和恢复组织平衡中和和消除的极点。本文研究了来自不同海藻(褐藻、红藻和绿藻)的藻类多糖的提取过程和其化学性质以及其对炎症过程的调节作用。
关键词: 大型海藻多糖、炎症、海藻、褐藻、红藻、绿藻。
Current Medicinal Chemistry
Title:Algae Polysaccharides’ Chemical Characterization and their Role in the Inflammatory Process
Volume: 24 Issue: 2
Author(s): Noelia Florez, Maria Jesus Gonzalez-Munoz, Daniela Ribeiro, Eduarda Fernandes, Herminia Dominguez, Marisa Freitas.
Affiliation:
关键词: 大型海藻多糖、炎症、海藻、褐藻、红藻、绿藻。
摘要: Polysaccharides are abundant components in marine macroalgae with potential applications in different areas such as pharmaceutical, biomedical, cosmetics and nutrition. The current interest in these compounds is due to their known bioactivities, conferred by their antiallergic, neuroprotective, gastroprotective, cardioprotective, cytotoxic, anticoagulant/antithrombotic, antiviral, antilipidemic, antinociceptive, and immunomodulatory properties, making them promising bioactive products and biomaterials. The inflammatory process is a complex event mediated by the immune system that culminates in the neutralization and elimination of the offending insult protecting the host and restoring tissue homeostasis. This review focuses on the extraction procedures and chemical characterization of polysaccharides from different classes of algae (Phaeophyceae, Rhodophyceae and Chlorophyceae) and on the studies on their inflammatory process modulatory effect.
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Cite this article as:
Noelia Florez, Maria Jesus Gonzalez-Munoz, Daniela Ribeiro, Eduarda Fernandes, Herminia Dominguez, Marisa Freitas. , Algae Polysaccharides’ Chemical Characterization and their Role in the Inflammatory Process, Current Medicinal Chemistry 2017; 24 (2) . https://dx.doi.org/10.2174/0929867323666161028160416
DOI https://dx.doi.org/10.2174/0929867323666161028160416 |
Print ISSN 0929-8673 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-533X |
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