A Short and Efficient Synthesis of the Selective H4 Receptor Agonist 4- Methylhistamine

Title: A Short and Efficient Synthesis of the Selective H4 Receptor Agonist 4- Methylhistamine

Volume: 6 Issue: 1

Author(s): Mirko Rivara, Valentina Zuliani, Pier V. Plazzi and Fabrizio Bordi

Affiliation:

Keywords: 4-methylhistamine, histamine, H4-receptor, n-butyllithium, H4-agonist, yield

Abstract: An efficient synthesis of the selective H4 receptor agonist 4-methylhistamine is described. This approach can be used to prepare, without purification steps and in high yield, significant quantities of the product, useful as pharmacological tool to investigate the physiological roles of the histamine H4 receptor.

Cite this article as:

Rivara Mirko, Zuliani Valentina, Plazzi V. Pier and Bordi Fabrizio, A Short and Efficient Synthesis of the Selective H4 Receptor Agonist 4- Methylhistamine, Letters in Organic Chemistry 2009; 6 (1) . https://dx.doi.org/10.2174/157017809787003223