基于纳米结构材料的电化学免疫传感器用于检测前列腺特异性抗原：综述

Title:Electrochemical Immunosensors Based on Nanostructured Materials for Sensing of Prostate-Specific Antigen: A Review

Volume: 28 Issue: 20

关键词: 前列腺特异性抗原、癌症标志物、免疫传感器、免疫测定、纳米材料、纳米技术。

摘要: The prostate-specific antigen (PSA) has been considered a crucial serological marker for distinguishing prostate based cancer. This survey shows recent progress in the construction of nanomaterial-based electrochemical immunosensors for a PSA. This review (from 2015 to 2020) reports the latest progress in PSA sensing based on the employ of different types of nanostructured materials. The most popular used nanostructured materials are metal, metal oxide, carbon-based nanomaterials, and their hybrid architectures utilized for distinct amplification protocols. In this review, the electrochemical immunosensors for prostate-specific antigen sensing are classified into three categories such as sandwich type@labeled, label free@nonlabeled and aptamer-based electrochemical immunosensor.

Cite this article as:

Electrochemical Immunosensors Based on Nanostructured Materials for Sensing of Prostate-Specific Antigen: A Review, Current Medicinal Chemistry 2021; 28 (20) . https://dx.doi.org/10.2174/0929867328666201124151821