Abstract
Gestational hypertension, preeclampsia, and diabetes are all associated with increased risks of poor maternal and perinatal outcome. In preeclampsia, exaggerated responses of insulin resistance, altered immune responses and inflammatory pathway activation are reminiscent of metabolic syndrome, and also are evident in gestational diabetes mellitus. Poor glycaemic control, preexisting hypertension and diabetic renal disease increase a diabetic woman’s risk for preeclampsia and associated maternal and fetal complications. In this short review, the possible link between diabetes and gestational hypertension is discussed.
Keywords: Diabetes, hypertension, pregnancy, insulin resistance, metabolic syndrome, glucose intolerance, pathophysiologic mechanisms, Placental secretion
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