Abstract
The role of polyphenols in the cardiovascular diseases prevention is still a matter of scientific discussion. However, recent clinical studies indicate that intake of anthocyanins and in a lesser extent procyanidins can participate in prevention of hypertension and type 2 diabetes. Fruits of Aronia melanocarpa (chokeberry) are known to be a reach source of these polyphenols. Moreover, its extracts were shown to express strong antioxidant, antiinflammatory, vasorelaxant and antithrombotic properties. The aim of the review is to summarize the results of the hitherto research regarding the biological effects at the molecular and clinical level.
Keywords: Aronia melanocarpa, chokeberry, anthocyanins, polyphenols, cardiovascular diseases, prevention.
Current Pharmaceutical Design
Title:Cardioprotective effects of Aronia melanocarpa anthocynanins. From laboratory experiments to clinical practice.
Volume: 22 Issue: 2
Author(s): Andrzej Parzonko and Marek Naruszewicz
Affiliation:
Keywords: Aronia melanocarpa, chokeberry, anthocyanins, polyphenols, cardiovascular diseases, prevention.
Abstract: The role of polyphenols in the cardiovascular diseases prevention is still a matter of scientific discussion. However, recent clinical studies indicate that intake of anthocyanins and in a lesser extent procyanidins can participate in prevention of hypertension and type 2 diabetes. Fruits of Aronia melanocarpa (chokeberry) are known to be a reach source of these polyphenols. Moreover, its extracts were shown to express strong antioxidant, antiinflammatory, vasorelaxant and antithrombotic properties. The aim of the review is to summarize the results of the hitherto research regarding the biological effects at the molecular and clinical level.
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Cite this article as:
Parzonko Andrzej and Naruszewicz Marek, Cardioprotective effects of Aronia melanocarpa anthocynanins. From laboratory experiments to clinical practice., Current Pharmaceutical Design 2016; 22 (2) . https://dx.doi.org/10.2174/1381612822666151112152143
DOI https://dx.doi.org/10.2174/1381612822666151112152143 |
Print ISSN 1381-6128 |
Publisher Name Bentham Science Publisher |
Online ISSN 1873-4286 |
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