Abstract
Diabetes Retinopathy (DR) is one of the main complications due to diabetes. DR will damage the retinal capillaries and block them, which causes the loss of vision. Different drugs and therapies are used for the treatment and prevention of the DR. The most commonly used treatment is laser technology and combination therapy, along with some drugs. But these drugs possess side effects in the form of cataract, glaucoma, and complete blindness of the eye. The main strategy to overcome In DR, medicines with minimum side effects or maximum therapeutic effects are used. This article emphasizes the current strategy used for the treatment of DR with allopathic as well as herbal drugs.
Keywords: Diabetes, diabetic retinopathy, herbal drugs, laser therapy, vision, drug.
Graphical Abstract
[http://dx.doi.org/10.1016/S0161-6420(03)00475-5] [PMID: 13129861]
[http://dx.doi.org/10.1016/j.bbadis.2017.01.016] [PMID: 28130199]
[http://dx.doi.org/10.1088/0957-4484/20/50/505101] [PMID: 19923650]
[http://dx.doi.org/10.1038/gt.2008.185] [PMID: 19194480]
[http://dx.doi.org/10.1073/pnas.0908561106] [PMID: 19822744]
[http://dx.doi.org/10.1208/s12248-010-9183-3] [PMID: 20437123]
[http://dx.doi.org/10.1111/j.1600-0420.2007.00885.x] [PMID: 17645424]
[http://dx.doi.org/10.2174/1389200033489488] [PMID: 12769666]
[http://dx.doi.org/10.1089/108076804772745419] [PMID: 15006154]
[http://dx.doi.org/10.1167/iovs.08-2370] [PMID: 18757508]
[http://dx.doi.org/10.1136/bjo.2009.169326] [PMID: 20813755]
[http://dx.doi.org/10.7860/JCDR/2017/20946.10294] [PMID: 28892938]
[http://dx.doi.org/10.4103/0301-4738.178144] [PMID: 26953022]
[http://dx.doi.org/10.1155/2017/2698975] [PMID: 28845303]
[http://dx.doi.org/10.1159/000487474] [PMID: 30111992]
[http://dx.doi.org/10.1136/bjophthalmol-2016-309219] [PMID: 27941046]
[http://dx.doi.org/10.2147/OPTH.S34200] [PMID: 23576864]
[http://dx.doi.org/10.1081/DDC-120002997] [PMID: 12056529]
[http://dx.doi.org/10.3390/scipharm86020016] [PMID: 29677103]
[http://dx.doi.org/10.1038/s41433-018-0055-x] [PMID: 29503450]
[http://dx.doi.org/10.2337/dc16-2641] [PMID: 28223445]
[PMID: 29351207]
[http://dx.doi.org/10.1155/2018/2801450] [PMID: 29854819]
[http://dx.doi.org/10.1111/dme.13596] [PMID: 29405370]
[http://dx.doi.org/10.1155/2013/636053] [PMID: 24348712]
[http://dx.doi.org/10.1016/j.exer.2016.08.005] [PMID: 27523466]
[http://dx.doi.org/10.12659/MSM.883895] [PMID: 23619778]
[http://dx.doi.org/10.2337/diabetes.50.7.1636] [PMID: 11423486]
[http://dx.doi.org/10.2337/diabetes.51.9.2826] [PMID: 12196477]
[http://dx.doi.org/10.1007/s00281-008-0111-x] [PMID: 18340447]
[http://dx.doi.org/10.2337/diabetes.54.12.3418] [PMID: 16306357]
[http://dx.doi.org/10.1016/j.mvr.2011.09.001] [PMID: 21945644]
[http://dx.doi.org/10.14336/AD.2017.0816] [PMID: 29344421]
[http://dx.doi.org/10.1016/j.jdiacomp.2011.11.004] [PMID: 22226482]
[http://dx.doi.org/10.1021/pr9006415] [PMID: 19845401]
[http://dx.doi.org/10.1111/j.1476-5381.2010.00840.x] [PMID: 20718738]
[http://dx.doi.org/10.1097/HJH.0b013e3283013b6e] [PMID: 18551021]
[http://dx.doi.org/10.1016/S0140-6736(97)06209-0] [PMID: 9433426]
[http://dx.doi.org/10.1517/14728210802584035] [PMID: 19046134]
[http://dx.doi.org/10.2174/1871525711311010006] [PMID: 22721439]
[PMID: 24379904]
[http://dx.doi.org/10.1186/1743-7075-4-8] [PMID: 17437639]
[http://dx.doi.org/10.1111/jphp.12683] [PMID: 28124440]
[http://dx.doi.org/10.1016/0378-8741(90)90001-A] [PMID: 2123954]
[http://dx.doi.org/10.1016/j.ophtha.2010.09.029] [PMID: 21232801]
[http://dx.doi.org/10.1136/bjo.2007.129122] [PMID: 17965109]
[http://dx.doi.org/10.1016/j.ajo.2007.12.031] [PMID: 18328456]
[http://dx.doi.org/10.1097/IAE.0b013e3181b094b7] [PMID: 19672218]
[http://dx.doi.org/10.1097/IAE.0b013e31819a5fc2] [PMID: 19262436]
[http://dx.doi.org/10.1056/NEJMoa062655] [PMID: 17021319]
[http://dx.doi.org/10.1097/IAE.0b013e3181a2f42a] [PMID: 19430280]
[http://dx.doi.org/10.1016/j.nano.2012.03.004] [PMID: 22465498]
[PMID: 24634856]
[http://dx.doi.org/10.1016/j.colsurfb.2014.09.042] [PMID: 25303852]
[http://dx.doi.org/10.1016/j.ijpharm.2010.03.034] [PMID: 20362042]
[http://dx.doi.org/10.1002/jps.23251] [PMID: 22767401]
[http://dx.doi.org/10.1016/j.jconrel.2004.09.015] [PMID: 15653131]
[http://dx.doi.org/10.1002/jps.24588] [PMID: 26227825]
[http://dx.doi.org/10.1167/iovs.14-16250] [PMID: 26193917]
[http://dx.doi.org/10.1089/adt.2018.898] [PMID: 30835139]