Abstract
Polycyclic aromatic hydrocarbons (PAHs), regarded as a class of hazardous pollutants due to their persistence and toxicity, are ubiquitous in the environment. Much research has been conducted on aerobic microbial degradation of some PAHs and determination of the degradation pathways for which synthesis of metabolic intermediates and metabolites is required. This mini-review briefly summarizes synthesis of commercially unavailable metabolites of phenanthrene, anthracene, pyrene, fluoranthene, and benzo[a]pyrene.
Keywords: Polycyclic aromatic hydrocarbons, PAH, Microbial degradation, Metabolites, biodegradation, metabolism, catabolism
Mini-Reviews in Organic Chemistry
Title: Synthesis of Metabolites of Polycyclic Aromatic Hydrocarbons
Volume: 7 Issue: 2
Author(s): Ming Liu, Yongliang Cui, Yousheng Duan, Jiangchun Zhong, Wei Sun, Min Wang, Shangzhong Liu and Qing X. Li
Affiliation:
Keywords: Polycyclic aromatic hydrocarbons, PAH, Microbial degradation, Metabolites, biodegradation, metabolism, catabolism
Abstract: Polycyclic aromatic hydrocarbons (PAHs), regarded as a class of hazardous pollutants due to their persistence and toxicity, are ubiquitous in the environment. Much research has been conducted on aerobic microbial degradation of some PAHs and determination of the degradation pathways for which synthesis of metabolic intermediates and metabolites is required. This mini-review briefly summarizes synthesis of commercially unavailable metabolites of phenanthrene, anthracene, pyrene, fluoranthene, and benzo[a]pyrene.
Export Options
About this article
Cite this article as:
Liu Ming, Cui Yongliang, Duan Yousheng, Zhong Jiangchun, Sun Wei, Wang Min, Liu Shangzhong and Li Qing X., Synthesis of Metabolites of Polycyclic Aromatic Hydrocarbons, Mini-Reviews in Organic Chemistry 2010; 7 (2) . https://dx.doi.org/10.2174/157019310791065528
DOI https://dx.doi.org/10.2174/157019310791065528 |
Print ISSN 1570-193X |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6298 |
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
Related Articles
-
<i>Moringa</i> oleifera Leaf Extract Attenuates Pb Acetate-induced Testicular Damage in Rats
Combinatorial Chemistry & High Throughput Screening Isoliquiritigenin Inhibits Proliferation and Induces Apoptosis via Alleviating Hypoxia and Reducing Glycolysis in Mouse Melanoma B16F10 Cells
Recent Patents on Anti-Cancer Drug Discovery Antiulcer Activity of Lemon (Citrus limon) Fruit Juice and Its Interaction with Conventionally used Antiulcer Drugs in Rats
The Natural Products Journal Drug Tissue Distribution: Study Methods and Therapeutic Implications
Current Pharmaceutical Design Epigenetic Modifications in Acute Lymphoblastic Leukemia: From Cellular Mechanisms to Therapeutics
Current Gene Therapy Application of In Vivo Animal Models to Characterize the Pharmacokinetic and Pharmacodynamic Properties of Drug Candidates in Discovery Settings
Combinatorial Chemistry & High Throughput Screening Biomedical Applications of Nanomaterials Containing Gadolinium
Current Inorganic Chemistry (Discontinued) Immobilization and Detection Strategies for Multifunctional Glycochips
Current Drug Targets Application of High-Throughput, Molecular-Targeted Screening to Anticancer Drug Discovery
Current Topics in Medicinal Chemistry Traditional Chinese Medicine - Sea Urchin
Mini-Reviews in Medicinal Chemistry Advancements in Predictive In Silico Models for ADME
Current Chemical Biology Chemoradiotherapy in Rectal Cancer
Current Drug Therapy New Perspectives for the Diagnosis of Alzheimers Disease
Recent Patents on CNS Drug Discovery (Discontinued) A Meta-Analysis of Proteomic Blood Markers of Colorectal Cancer
Current Medicinal Chemistry Preclinical Profile of Bacopasides From Bacopa monnieri (BM) As An Emerging Class of Therapeutics for Management of Chronic Pains
Current Medicinal Chemistry A Synopsis on the Role of Human Papilloma Virus Infection in Cervical Cancer
Current Drug Metabolism MicroRNAs and Peroxisome Proliferator-Activated Receptors Governing the Differentiation of Mesenchymal Stem Cells
Current Stem Cell Research & Therapy Bispidine as a Privileged Scaffold
Current Topics in Medicinal Chemistry Understanding the Tumor Metabolic Phenotype in the Genomic Era
Current Molecular Medicine Antibacterial Agents Against Methicillin-Resistant Staphylococcus aureus (MRSA) and Vancomycin-Resistant Enterococci (VRE)
Anti-Infective Agents in Medicinal Chemistry