Abstract
Polycyclic aromatic hydrocarbons (PAHs), regarded as a class of hazardous pollutants due to their persistence and toxicity, are ubiquitous in the environment. Much research has been conducted on aerobic microbial degradation of some PAHs and determination of the degradation pathways for which synthesis of metabolic intermediates and metabolites is required. This mini-review briefly summarizes synthesis of commercially unavailable metabolites of phenanthrene, anthracene, pyrene, fluoranthene, and benzo[a]pyrene.
Keywords: Polycyclic aromatic hydrocarbons, PAH, Microbial degradation, Metabolites, biodegradation, metabolism, catabolism
Mini-Reviews in Organic Chemistry
Title: Synthesis of Metabolites of Polycyclic Aromatic Hydrocarbons
Volume: 7 Issue: 2
Author(s): Ming Liu, Yongliang Cui, Yousheng Duan, Jiangchun Zhong, Wei Sun, Min Wang, Shangzhong Liu and Qing X. Li
Affiliation:
Keywords: Polycyclic aromatic hydrocarbons, PAH, Microbial degradation, Metabolites, biodegradation, metabolism, catabolism
Abstract: Polycyclic aromatic hydrocarbons (PAHs), regarded as a class of hazardous pollutants due to their persistence and toxicity, are ubiquitous in the environment. Much research has been conducted on aerobic microbial degradation of some PAHs and determination of the degradation pathways for which synthesis of metabolic intermediates and metabolites is required. This mini-review briefly summarizes synthesis of commercially unavailable metabolites of phenanthrene, anthracene, pyrene, fluoranthene, and benzo[a]pyrene.
Export Options
About this article
Cite this article as:
Liu Ming, Cui Yongliang, Duan Yousheng, Zhong Jiangchun, Sun Wei, Wang Min, Liu Shangzhong and Li Qing X., Synthesis of Metabolites of Polycyclic Aromatic Hydrocarbons, Mini-Reviews in Organic Chemistry 2010; 7 (2) . https://dx.doi.org/10.2174/157019310791065528
DOI https://dx.doi.org/10.2174/157019310791065528 |
Print ISSN 1570-193X |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6298 |
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
Related Articles
-
Comprehensive Analysis of the mRNA-lncRNA Co-expression Profile and ceRNA Networks Patterns in Chronic Hepatitis B
Current Genomics Potential Anticancer Agents. I. Synthesis of Isoxazole Moiety Containing Quinazoline Derivatives and Preliminarily in vitro Anticancer Activity
Anti-Cancer Agents in Medicinal Chemistry Artificial Intelligence (AI) in Drugs and Pharmaceuticals
Combinatorial Chemistry & High Throughput Screening Furocoumarins from Cnidium monnieri Act as Peroxisome Proliferatoractivated R and Farnesoid X Receptor Agonists
Mini-Reviews in Organic Chemistry Optical Chemical Biosensors for High Throughput Screening of Drugs
Combinatorial Chemistry & High Throughput Screening Curcumin: Structure-Activity Relationship Towards its Role as a Versatile Multi-Targeted Therapeutics
Mini-Reviews in Organic Chemistry Recent Advances in the Applications of SAMP/RAMP as Chiral Auxiliaries in Asymmetric Synthesis
Current Organic Synthesis A Random Forest-Induced Distance-Based Measure of Physiologic al Dysregulation
Current Aging Science A Novel Platinum-based Compound with Preferential Cytotoxic Activity against a Panel of Cancer Cell Lines
Anti-Cancer Agents in Medicinal Chemistry Formulation and Evaluation of Solid Lipid Nanoparticles of Quetiapine Fumarate and Quetiapine Hemifumarate for Brain Delivery in Rat Model
Pharmaceutical Nanotechnology The Plasma Levels of hsa-miR-19b-3p, hsa-miR-125b-5p, and hsamiR- 320c in Patients with Asthma, COPD and Asthma-COPD Overlap Syndrome (ACOS)
MicroRNA AP5346 (ProLindac™), A DACH Platinum Polymer Conjugate in Phase II Trials Against Ovarian Cancer
Current Bioactive Compounds The New Era of Bioluminescence Resonance Energy Transfer Technology
Current Pharmaceutical Biotechnology Unconventional Interaction Forces in Protein and Protein-ligand Systems and their Impacts to Drug Design
Current Topics in Medicinal Chemistry Systemic Redox Biomarkers in Neurodegenerative Diseases
Current Drug Metabolism NF-κB Down–regulation and PARP Cleavage by novel 3-α-butyryloxy-β-boswellic Acid Results in Cancer Cell Specific Apoptosis and in vivo Tumor Regression
Anti-Cancer Agents in Medicinal Chemistry Expression and Characterisation of Recombinant Molecules in Transgenic Soybean
Current Pharmaceutical Design iPGK-PseAAC: Identify Lysine Phosphoglycerylation Sites in Proteins by Incorporating Four Different Tiers of Amino Acid Pairwise Coupling Information into the General PseAAC
Medicinal Chemistry Structure-Based Design of Benzimidazole Sugar Conjugates: Synthesis, SAR and In Vivo Anti-inflammatory and Analgesic Activities
Medicinal Chemistry Lycorine and its Derivatives for Anticancer Drug Design
Mini-Reviews in Medicinal Chemistry