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Current Protein & Peptide Science

Editor-in-Chief

ISSN (Print): 1389-2037
ISSN (Online): 1875-5550

Recent Progress in Research on Ribosome Inactivating Proteins

Author(s): T. B. Ng, Jack Ho Wong and Hexiang Wang

Volume 11, Issue 1, 2010

Page: [37 - 53] Pages: 17

DOI: 10.2174/138920310790274662

Price: $65

Abstract

The intent of this article is to review recent literature on ribosome inactivating proteins (RIPs) including isolation and characterization of new RIPs, studies on the crystal structures and mechanisms of actions of RIPs, the use of saporin-based neurotoxins to selectively lesion cholinergic neurons in neuroscience research, and the use of RIP-based conjugates and immunotoxins in anticancer therapy.


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