Oncomirs: From Tumor Biology to Molecularly Targeted Anticancer Strategies

Title: Oncomirs: From Tumor Biology to Molecularly Targeted Anticancer Strategies

Volume: 9 Issue: 1

Author(s): Simone Mocellin, Sandro Pasquali and Pierluigi Pilati

Affiliation:

Keywords: MicroRNA, miRNA, oncomirs, cancer biology, molecular targets, anticancer therapeutics

Abstract: Deregulation of microRNA (miRNA) promotes carcinogenesis, as these molecules can act as oncogenes or tumor suppressor genes. Here we provide an overview of miRNA biology, discuss the most recent findings on miRNA and cancer development/progression, and report on how tumor-related miRNAs (oncomirs) are being used to develop novel cancer specific therapeutic approaches.

Cite this article as:

Mocellin Simone, Pasquali Sandro and Pilati Pierluigi, Oncomirs: From Tumor Biology to Molecularly Targeted Anticancer Strategies, Mini-Reviews in Medicinal Chemistry 2009; 9 (1) . https://dx.doi.org/10.2174/138955709787001802