Which Treatment for Nonalcoholic Fatty Liver Disease?

Title: Which Treatment for Nonalcoholic Fatty Liver Disease?

Volume: 8 Issue: 8

Author(s): S. Moscatiello, R. Marzocchi, N. Villanova, E. Bugianesi and G. Marchesini

Affiliation:

Keywords: Orlistat, weight loss, Metformin, statins, Lipid peroxidation, diabetes

Abstract: Subjects with nonalcoholic fatty liver disease are at risk of progressive liver failure. Lifestyle changes including weight-loss strategies and increased physical activity remain the first-line approach, but a few pharmacological treatments have also been successfully tested. Several drugs improve biochemistry, only a few improve histology; in all cases, the results were not sustained after treatment stop. Pharmacological treatment is not so far indicated outside controlled clinical trials with histological outcomes.

Cite this article as:

Moscatiello S., Marzocchi R., Villanova N., Bugianesi E. and Marchesini G., Which Treatment for Nonalcoholic Fatty Liver Disease?, Mini-Reviews in Medicinal Chemistry 2008; 8 (8) . https://dx.doi.org/10.2174/138955708784912193