Abstract
Naproxen or 2-(6-methoxy naphthalen-2-yl)propionic acid participated in trifluoroacetic anhydride/ phosphoric acid mediated C-C bond forming reaction in a regioselective fashion when treated with a variety of arene or heteroarene under a solvent-free condition affording novel 1-aryl/heteroaryl substituted 2-(6-methoxy naphthalen-2-yl)propan-1-ones in good yields.
Keywords: Naproxen, acylation, trifluoroacetic anhydride, phosphoric acid
Letters in Organic Chemistry
Title: Novel Naproxen Derivatives: Lewis Acid/Transition-metal Free Synthesis via C-C Bond Forming Reaction
Volume: 4 Issue: 4
Author(s): Sarbani Pal, P. Bindu, Pragnyadhar Reddy Venna and P. K. Dubey
Affiliation:
Keywords: Naproxen, acylation, trifluoroacetic anhydride, phosphoric acid
Abstract: Naproxen or 2-(6-methoxy naphthalen-2-yl)propionic acid participated in trifluoroacetic anhydride/ phosphoric acid mediated C-C bond forming reaction in a regioselective fashion when treated with a variety of arene or heteroarene under a solvent-free condition affording novel 1-aryl/heteroaryl substituted 2-(6-methoxy naphthalen-2-yl)propan-1-ones in good yields.
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Cite this article as:
Sarbani Pal , P. Bindu , Pragnyadhar Reddy Venna and P. K. Dubey , Novel Naproxen Derivatives: Lewis Acid/Transition-metal Free Synthesis via C-C Bond Forming Reaction, Letters in Organic Chemistry 2007; 4 (4) . https://dx.doi.org/10.2174/157017807781024255
DOI https://dx.doi.org/10.2174/157017807781024255 |
Print ISSN 1570-1786 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6255 |
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