Abstract
The influence of substituents on the yields of the synthesis of seven catechines analogues has been studied. 3-Flavene formation is favoured by electron donors substituents on the A and B rings. Yields of the hydroboration reaction are increased by electron donor substituents on the A ring, while substituents on the B ring do not affect the reaction outcome.
Keywords: Gallocatechin, catechins, total synthesis, structure-reactivity study, EGCG
Letters in Organic Chemistry
Title: Synthesis of Gallocatechin-3-Gallate Analogues
Volume: 4 Issue: 4
Author(s): Nadia Vaiana, Luca Rizzi, Maria G. Pezzano, Roberto Restelli, Filippo Rota, Silvia Stefanini, Silvia Vicentini and Sergio Romeo
Affiliation:
Keywords: Gallocatechin, catechins, total synthesis, structure-reactivity study, EGCG
Abstract: The influence of substituents on the yields of the synthesis of seven catechines analogues has been studied. 3-Flavene formation is favoured by electron donors substituents on the A and B rings. Yields of the hydroboration reaction are increased by electron donor substituents on the A ring, while substituents on the B ring do not affect the reaction outcome.
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Cite this article as:
Nadia Vaiana , Luca Rizzi , Maria G. Pezzano , Roberto Restelli , Filippo Rota , Silvia Stefanini , Silvia Vicentini and Sergio Romeo , Synthesis of Gallocatechin-3-Gallate Analogues, Letters in Organic Chemistry 2007; 4 (4) . https://dx.doi.org/10.2174/157017807781024291
DOI https://dx.doi.org/10.2174/157017807781024291 |
Print ISSN 1570-1786 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6255 |
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