Abstract
Herein we give a brief account of the efforts our group made in recent years to discover novel enzymes and utilize them by bioprocess engineering techniques for stereoselective synthesis of various enantiomerically pure chiral chemicals with high value in a greener manner. Included are discussions on oxidoreductases, expoxide hydrolases and glucosidases in whole cells or isolated form from microorganisms or plants.
Keywords: Target-directed discovery, Biocatalysis, Oxidoreductases, Expoxide hydrolases, Glucosidases, Bioprocess engineering, Reductases, Rhodotorula sp. AS2.2241, Bacillus sp. ECU0013, Adzuki Bean Ketone Reductases, Pseudomonas putida ECU1009, Glycolate Oxidase, Alcaligenes sp. ECU0401, Rhodococcus sp. ECU0066, EPOXIDE HYDROLASES
Current Organic Chemistry
Title: Target-directed Discovery and Bioprocess Engineering of New Enzymes for Environmentally Benign Production of High-Value Chiral Chemicals
Volume: 15 Issue: 14
Author(s): Ling Ou, Hui-Lei Yu and Jian-He Xu
Affiliation:
Keywords: Target-directed discovery, Biocatalysis, Oxidoreductases, Expoxide hydrolases, Glucosidases, Bioprocess engineering, Reductases, Rhodotorula sp. AS2.2241, Bacillus sp. ECU0013, Adzuki Bean Ketone Reductases, Pseudomonas putida ECU1009, Glycolate Oxidase, Alcaligenes sp. ECU0401, Rhodococcus sp. ECU0066, EPOXIDE HYDROLASES
Abstract: Herein we give a brief account of the efforts our group made in recent years to discover novel enzymes and utilize them by bioprocess engineering techniques for stereoselective synthesis of various enantiomerically pure chiral chemicals with high value in a greener manner. Included are discussions on oxidoreductases, expoxide hydrolases and glucosidases in whole cells or isolated form from microorganisms or plants.
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Cite this article as:
Ou Ling, Yu Hui-Lei and Xu Jian-He, Target-directed Discovery and Bioprocess Engineering of New Enzymes for Environmentally Benign Production of High-Value Chiral Chemicals, Current Organic Chemistry 2011; 15 (14) . https://dx.doi.org/10.2174/138527211796150598
DOI https://dx.doi.org/10.2174/138527211796150598 |
Print ISSN 1385-2728 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5348 |
Call for Papers in Thematic Issues
Catalytic C-H bond activation as a tool for functionalization of heterocycles
The major topic is the functionalization of heterocycles through catalyzed C-H bond activation. The strategies based on C-H activation not only provide straightforward formation of C-C or C-X bonds but, more importantly, allow for the avoidance of pre-functionalization of one or two of the cross-coupling partners. The beneficial impact of ...read more
Chemistry and Biology of Carbohydrates
Carbohydrates are one of the most abundant natural products and are considered to be extremely important biomolecules for their ever-increasing impact on chemistry and biology. Their role in several important biological processes, notably energy storage, transport, modulation of protein function, intercellular adhesion, malignant transformation, signal transduction, viral, and bacterial cell ...read more
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