Abstract
The persistence of pesticides and drugs in products destined for human consumption is of great concern, in particular because of their potential carcinogenic character. However, often the transformation products formed through degradation processes possess higher toxicity than the parent compounds. It is then of primary importance not only to achieve their abatement (through purification procedures), but also to detect and identify the formed by-products, in order to evaluate their formation kinetics, stability and toxicity. For this purpose, in the present review we will study in depth, the transformation pathways followed by molecules belonging to different classes of compounds, i.e pesticides, drugs and dyes and their derivatives in photo-assisted, environmental and biological studies, where they have been identified and characterized by means of hyphenated techniques. Particular attention will be paid to degradation simulating models, such as the photocatalytic process on titanium dioxide.
Keywords: pesticides, drugs, dyes, hplc/ms, gc/ms, photocatalysis
Current Analytical Chemistry
Title: Identification of Degradation Products by Adopting GC or HPLC/MS Techniques
Volume: 1 Issue: 3
Author(s): Paola Calza, Claudio Medana, Claudio Baiocchi and Ezio Pelizzetti
Affiliation:
Keywords: pesticides, drugs, dyes, hplc/ms, gc/ms, photocatalysis
Abstract: The persistence of pesticides and drugs in products destined for human consumption is of great concern, in particular because of their potential carcinogenic character. However, often the transformation products formed through degradation processes possess higher toxicity than the parent compounds. It is then of primary importance not only to achieve their abatement (through purification procedures), but also to detect and identify the formed by-products, in order to evaluate their formation kinetics, stability and toxicity. For this purpose, in the present review we will study in depth, the transformation pathways followed by molecules belonging to different classes of compounds, i.e pesticides, drugs and dyes and their derivatives in photo-assisted, environmental and biological studies, where they have been identified and characterized by means of hyphenated techniques. Particular attention will be paid to degradation simulating models, such as the photocatalytic process on titanium dioxide.
Export Options
About this article
Cite this article as:
Calza Paola, Medana Claudio, Baiocchi Claudio and Pelizzetti Ezio, Identification of Degradation Products by Adopting GC or HPLC/MS Techniques, Current Analytical Chemistry 2005; 1 (3) . https://dx.doi.org/10.2174/157341105774573992
DOI https://dx.doi.org/10.2174/157341105774573992 |
Print ISSN 1573-4110 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6727 |
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
- Announcements
Related Articles
-
Atopic Dermatitis and Cytokines: The Immunoregulatory and Therapeutic Implications of Cytokines in Atopic Dermatitis - Part II: Negative Regulation and Cytokine Therapy in Atopic Dermatitis
Recent Patents on Inflammation & Allergy Drug Discovery Molecular Recognition of Tachykinin Receptor Selective Agonists: Insights from Structural Studies
Mini-Reviews in Medicinal Chemistry Is Low Vitamin D Status A Risk Factor For Food Allergy? Current Evidence And Future Directions
Mini-Reviews in Medicinal Chemistry Anti-Inflammatory Drug Effects on Apoptosis of Eosinophil Granulocytes Derived from Murine Bone-Marrow: Cellular Mechanisms as Related to Lineage, Developmental Stage and Hemopoietic Environment
Anti-Inflammatory & Anti-Allergy Agents in Medicinal Chemistry Anti-Respiratory Syncytial Virus Mechanism of <i>Houttuynia cordata</i> Thunb Exploration based on Network Pharmacology
Combinatorial Chemistry & High Throughput Screening Defense-related Proteins from Chelidonium majus L. as Important Components of its Latex
Current Protein & Peptide Science Ketoprofen Allergic Reactions
Recent Patents on Inflammation & Allergy Drug Discovery Fluoride Effects: The Two Faces of Janus
Current Medicinal Chemistry Immunomodulatory and Anti-inflammatory Effects of Thymoquinone
Cardiovascular & Hematological Disorders-Drug Targets Tachykinins in the Respiratory Tract
Current Drug Targets The Re-Emergence of Aerosol Gene Delivery: A Viable Approach to Lung Cancer Therapy
Current Cancer Drug Targets Extracellular Vesicles as Innovative Tools for Assessing Adverse Effects of Immunosuppressant Drugs
Current Medicinal Chemistry Targeting Mitogen-Activated Protein Kinases for Asthma
Current Drug Targets Role of IL-17F in the Pathogenesis of Psoriasis
Current Immunology Reviews (Discontinued) Editorial: New Insights into a Classical Pathway: Key Roles of the Mevalonate Cascade in Different Diseases (Part II)
Current Molecular Pharmacology RNA Splicing Manipulation: Strategies to Modify Gene Expression for a Variety of Therapeutic Outcomes
Current Gene Therapy The Occurrence of Bisphenol A, Phthalates, Parabens and Other Environmental Phenolic Compounds in House Dust: A Review
Current Organic Chemistry Prevalence of Intestinal Parasites among Patients with Chronic Urticaria in Northern Iran
Infectious Disorders - Drug Targets On the Cellular and Molecular Regulatory Transcriptional Mechanisms and Responsive Putative Pathways to Inflammatory Oxidative Stress Revisited: Current Immunological Breakthroughs and Views at a Glance
Anti-Inflammatory & Anti-Allergy Agents in Medicinal Chemistry Epigenetic Regulation in Particulate Matter-Mediated Cardiopulmonary Toxicities: A Systems Biology Perspective
Current Pharmacogenomics and Personalized Medicine