Abstract
Since the discovery of (2α,3β)-2,3-dihydroxyolean-12-en-28-oic acid, also known as maslinic acid, many studies have examined its biological activity, which has been shown to promote health and resist various diseases. This article focuses on previous research on maslinic acid and mainly reviews its reported effects on cardiovascular diseases, neuroprotection, diabetes, cancer, inflammation, and pathogens. Maslinic acid exerts positive effects on both cell and animal models of disease. Although its mechanism of action has not yet been completely elucidated, maslinic acid is feasible as a nutritional additive and has the potential to be developed as a drug.
Keywords: Maslinic acid, cardiovascular diseases, neuroprotection, diabetes, cancer, inflammation, pathogens.
Graphical Abstract
Current Drug Targets
Title:Review of the Biological Activity of Maslinic Acid
Volume: 22 Issue: 13
Author(s): Zhang Jing, Wang Rui, Li Ruihua, Yu Hao*Fang Hengtong*
Affiliation:
- Key Laboratory of Zoonosis Research, Ministry of Education, College of Animal Sciences, Jilin University, Changchun 130062,China
- Key Laboratory of Zoonosis Research, Ministry of Education, College of Animal Sciences, Jilin University, Changchun 130062,China
Keywords: Maslinic acid, cardiovascular diseases, neuroprotection, diabetes, cancer, inflammation, pathogens.
Abstract: Since the discovery of (2α,3β)-2,3-dihydroxyolean-12-en-28-oic acid, also known as maslinic acid, many studies have examined its biological activity, which has been shown to promote health and resist various diseases. This article focuses on previous research on maslinic acid and mainly reviews its reported effects on cardiovascular diseases, neuroprotection, diabetes, cancer, inflammation, and pathogens. Maslinic acid exerts positive effects on both cell and animal models of disease. Although its mechanism of action has not yet been completely elucidated, maslinic acid is feasible as a nutritional additive and has the potential to be developed as a drug.
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Cite this article as:
Jing Zhang, Rui Wang, Ruihua Li , Hao Yu *, Hengtong Fang *, Review of the Biological Activity of Maslinic Acid, Current Drug Targets 2021; 22 (13) . https://dx.doi.org/10.2174/1389450122666210308111159
DOI https://dx.doi.org/10.2174/1389450122666210308111159 |
Print ISSN 1389-4501 |
Publisher Name Bentham Science Publisher |
Online ISSN 1873-5592 |
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