Abstract
An efficient method has been developed for the synthesis of new pyrano[3,2-c] and pyrano[3,2-a]carbazole derivatives via a three-component reaction of 4-hydroxycarbazole or 2-hydroxycarbazole, isocyanides, and dialkylacetylenedicarboxylates. Noteworthy features of this protocol include mild reaction conditions, catalyst-free, high atom-economy and high yields.
Keywords: Pyanocarbazole, hydroxycarbazole, isocyanides, dialkylacetylenedicarboxylates, carbazole, multicomponent reaction.
Graphical Abstract
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