Prospective Plant Based Anticancer Lead Molecules

Title:Prospective Plant Based Anticancer Lead Molecules

Volume: 18 Issue: 30

Author(s): Prabhjot Kaur and Vikas Sharma*

Affiliation:

• University Institute of Pharma Sciences, Chandigarh University, National Highway 95, Chandigarh-Ludhiana Highway, Mohali, Punjab-140413,India

Keywords: Abietane, Fucoxanthin, Obovatol, Phytoconstituents, Anticancer, Lead molecules, Terpenoids.

Abstract: Nature has been a source of a wide range of products being utilized for the treatment of various diseases like malaria, cancer, diabetes etc. Among these, cancer is emerging as a leading cause of deaths worldwide and the development of cross-resistance to already established drugs increases the need for novel anticancer drugs. To discover novel anticancer molecules, it is a necessity to unearth the molecules which can act as anticancer agents. Taking natural products in vision, phytoconstituents like terpenoids, flavones, glycosides and alkaloids might act as a major source of lead molecules. Considering the anticancer prospectives of phytoconstituents, different unknown lead molecules are summarized in this review. The present review highlights the representative studies of plant-based anticancer agents which are classified as per their phytochemical nature. Furthermore, important key points along with important structure-activity relationships points regarding selected lead molecules are also discussed.

Cite this article as:

Kaur Prabhjot and Sharma Vikas *, Prospective Plant Based Anticancer Lead Molecules, Current Topics in Medicinal Chemistry 2018; 18 (30) . https://dx.doi.org/10.2174/1568026619666181224101132