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Current Radiopharmaceuticals

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ISSN (Print): 1874-4710
ISSN (Online): 1874-4729

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Review Article

Clinical Value of PET/CT in Staging Melanoma and Potential New Radiotracers

Author(s): Salvatore Annunziata*, Riccardo Laudicella, Federico Caobelli, Daniele A. Pizzuto and Young Aimn Working Group

Volume 13, Issue 1, 2020

Page: [6 - 13] Pages: 8

DOI: 10.2174/1874471012666191015094620

Price: $65

Abstract

Background: 18F-FDG PET/CT has been suggested as an effective tool to stage patients affected by melanoma. In the latest years, new radiopharmaceuticals have been proposed and the use of hybrid PET/ceCT has emerged.

Objective: To review recent evidence on the role of PET/CT in melanoma staging as well as its potential for future developments.

Methods: A comprehensive computer literature search of PubMed/MEDLINE was carried out to find relevant published articles concerning the feasibility of PET/CT in patients with malignant melanoma.

Results: Some recent studies about potentials and limitations of 18F-FDG PET/CT in staging melanoma, new PET radiotracers beyond 18F-FDG and application of hybrid PET/ceCT have been reviewed and discussed.

Conclusion: PET/CT plays an important role in the staging workup of patients affected by melanoma. New radiopharmaceuticals and hybrid PET/ceCT could improve the potential of this diagnostic tool in this field.

Keywords: PET-CT, CT, PET, 18F-FDG, melanoma, contrast.

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Graphical Abstract

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