Abstract
2,3-Dichloro-1,4-naphthoquinone is a special naphthoquinone with four electrophilic sites, useful for applications in organic synthesis and preparation of a diverse new compounds, such as 2,3-substituted derivatives and heterocycles, including those with the core naphthoquinone structure fused. It has also been used for the preparation of compounds for evaluation against several biological targets. This review will describe the most recent applications of 2,3-dichloro-1,4-naphthoquinone in organic synthesis.
Keywords: Quinones, synthetic applications, biological activity, heterocycles, cyclization reactions, nucleophilic substitutions, napthoquinone.
Graphical Abstract
Mini-Reviews in Organic Chemistry
Title:2,3-Dichloro-1,4-Naphthoquinone in Organic Synthesis: Recent Advances
Volume: 14 Issue: 5
Author(s): Luana da S. M. Forezi, Mariana F. C. Cardoso, Dora C. S. Costa, Fernando de C. da Silva and Vitor F. Ferreira*
Affiliation:
- Universidade Federal Fluminense, Departamento de Química Orgânica, Programa de Pós- Graduação em Química, Outeiro de São João Baptista, 24020-141 Niterói, RJ,Brazil
Keywords: Quinones, synthetic applications, biological activity, heterocycles, cyclization reactions, nucleophilic substitutions, napthoquinone.
Abstract: 2,3-Dichloro-1,4-naphthoquinone is a special naphthoquinone with four electrophilic sites, useful for applications in organic synthesis and preparation of a diverse new compounds, such as 2,3-substituted derivatives and heterocycles, including those with the core naphthoquinone structure fused. It has also been used for the preparation of compounds for evaluation against several biological targets. This review will describe the most recent applications of 2,3-dichloro-1,4-naphthoquinone in organic synthesis.
Export Options
About this article
Cite this article as:
Forezi da S. M. Luana, Cardoso F. C. Mariana, Costa C. S. Dora , da Silva de C. Fernando and Ferreira F. Vitor *, 2,3-Dichloro-1,4-Naphthoquinone in Organic Synthesis: Recent Advances, Mini-Reviews in Organic Chemistry 2017; 14 (5) . https://dx.doi.org/10.2174/1570193X14666170518125507
DOI https://dx.doi.org/10.2174/1570193X14666170518125507 |
Print ISSN 1570-193X |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6298 |
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
Related Articles
-
Subject Index to Volume 3
Current Medicinal Chemistry - Anti-Cancer Agents Mesenchymal Stem Cells: Key Actors in Tumor Niche
Current Stem Cell Research & Therapy Targeted Drugs and Nanomedicine: Present and Future
Current Pharmaceutical Design Cytochrome P450-Activated Prodrugs: Targeted Drug Delivery
Current Medicinal Chemistry Vascular Endothelial Growth Factor (VEGF) Signaling in Tumour Vascularization: Potential and Challenges
Current Vascular Pharmacology Approaches Targeting KV10.1 Open a Novel Window for Cancer Diagnosis and Therapy
Current Medicinal Chemistry Radioprotective Gene Therapy
Current Gene Therapy Anti-cancer Nitrogen-Containing Heterocyclic Compounds
Current Organic Chemistry Herpes Simplex Viruses in Antiviral Drug Discovery
Current Pharmaceutical Design The Chemokine System as a Therapeutic Target in Autoimmune Thyroid Diseases: A Focus on the Interferon-γ Inducible Chemokines and their Receptor
Current Pharmaceutical Design Epigenetic MicroRNA Regulation of Multiple Chromatin Functions: A Perspective in Cancer
Epigenetic Diagnosis & Therapy (Discontinued) Rediscovering Tocophersolan: A Renaissance for Nano-Based Drug Delivery and Nanotheranostic Applications
Current Drug Targets Detecting Growing Mammary Tumors with Monoclonal Antibodies Against Vascular Endothelial Growth Factor Receptor – 3
Current Radiopharmaceuticals Administration of Drug and Nutritional Components in Nano-Engineered Form to Increase Delivery Ratio and Reduce Current Inefficient Practice
Recent Patents on Drug Delivery & Formulation Metal Containing Cytostatics and Their Interaction with Cellular Thiol Compounds Causing Chemoresistance
Anti-Cancer Agents in Medicinal Chemistry Nanomedicine and its Application in Treatment of Microglia-mediated Neuroinflammation
Current Medicinal Chemistry Unleashing the Potential of Microbial Natural Products in Drug Discovery: Focusing on <i>Streptomyces</i> as Antimicrobials Goldmine
Current Topics in Medicinal Chemistry Biologically Active Selenophenes and Benzo[b]selenophenes
Current Organic Synthesis Anticancer Metallotherapeutics in Preclinical Development
Current Medicinal Chemistry Dendritic Cell Immunotherapy for Melanoma
Reviews on Recent Clinical Trials