Abstract
Background: In the treatment of Inflammatory Bowel Diseases (IBD) despite advances in medical therapies, surgery has maintained a leading role in the management of complications of the disease, as well as in cases of failure of medical therapy.
Objective: discuss the possible role for a personalization in debated fields of surgical treatment of Crohn's disease and ulcerative colitis.
Conclusions: Surgery has become more and more minimally invasive, struggling for a difficult balance between guidelines and personalized treatment tailored on the single patient's need. There is no room for fixed management for surgery in IBD. A tailored approach is key to better outcome in each specific patient.
Keywords: Crohn's disease, inflammatory bowel disease, surgery, personalization, tailored surgery, ulcerative colitis.
Graphical Abstract
Current Drug Targets
Title:Can Surgery for Inflammatory Bowel Disease be Personalized?
Volume: 19 Issue: 7
Author(s): Antonino Spinelli*, Alessandra Marano, Claudio Bacchelli, Nicolo Maria Mariani, Marco Montorsi and Paulo Gustavo Kotze
Affiliation:
- Department of Biomedical Sciences, Humanitas University, via Manzoni 113, 20089 Rozzano, Milano,Italy
Keywords: Crohn's disease, inflammatory bowel disease, surgery, personalization, tailored surgery, ulcerative colitis.
Abstract: Background: In the treatment of Inflammatory Bowel Diseases (IBD) despite advances in medical therapies, surgery has maintained a leading role in the management of complications of the disease, as well as in cases of failure of medical therapy.
Objective: discuss the possible role for a personalization in debated fields of surgical treatment of Crohn's disease and ulcerative colitis.
Conclusions: Surgery has become more and more minimally invasive, struggling for a difficult balance between guidelines and personalized treatment tailored on the single patient's need. There is no room for fixed management for surgery in IBD. A tailored approach is key to better outcome in each specific patient.
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Cite this article as:
Spinelli Antonino*, Marano Alessandra, Bacchelli Claudio, Mariani Maria Nicolo, Montorsi Marco and Kotze Gustavo Paulo, Can Surgery for Inflammatory Bowel Disease be Personalized?, Current Drug Targets 2018; 19 (7) . https://dx.doi.org/10.2174/1389450118666170105153646
DOI https://dx.doi.org/10.2174/1389450118666170105153646 |
Print ISSN 1389-4501 |
Publisher Name Bentham Science Publisher |
Online ISSN 1873-5592 |
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