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Mini-Reviews in Medicinal Chemistry

Editor-in-Chief

ISSN (Print): 1389-5575
ISSN (Online): 1875-5607

Central and Mucosal Immunities are Modified by Non Adsorbable Antibiotic Treatment in Uncomplicated Diverticular Disease

Author(s): F. Pandolfi, S. Frosali, L. Petruzziello, E.E. Newton and G. Costamagna

Volume 16, Issue 3, 2016

Page: [218 - 221] Pages: 4

DOI: 10.2174/1389557515666150722104035

Price: $65

Abstract

We review our experience on Rifaximin in uncomplicated diverticular disease. Our data show that a 2 week treatment induces modifications in the immune system: local mucosal lymphocytes with TLR-4 were increased. In the peripheral blood CD103 cells, which increased before treatment, returned to normal values after Rifaximin.

Keywords: Diverticular disease, rifaximin, mucosal immunity, TLR2, TLR4, T-lymphocytes.


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