Abstract
Lutetium-177 (177Lu) is a late entrant into the nuclear medicine therapy arena but is expected to become one of the most widely used therapeutic radionuclides. This paper analyses the reason for the increasing preference of 177Lu as a therapeutic radionuclide. While the radionuclidic properties favor its use for several therapeutic applications, the potential for large scale production of 177Lu is also an important aspect for its acceptability as a therapeutic radionuclide. This introductory discussion also summarizes some developing clinical uses and suggested future directions for applications of 177Lu.
Keywords: Antibodies, bone pain palliation, isotope production, Lutetium-177, peptides, targeted radionuclide therapy, therapeutic radiopharmaceuticals.
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Current Radiopharmaceuticals
Title:Evolving Important Role of Lutetium-177 for Therapeutic Nuclear Medicine
Volume: 8 Issue: 2
Author(s): Ambikalmajan M.R. Pillai and Furn F. (Russ) Knapp
Affiliation:
Keywords: Antibodies, bone pain palliation, isotope production, Lutetium-177, peptides, targeted radionuclide therapy, therapeutic radiopharmaceuticals.
Abstract: Lutetium-177 (177Lu) is a late entrant into the nuclear medicine therapy arena but is expected to become one of the most widely used therapeutic radionuclides. This paper analyses the reason for the increasing preference of 177Lu as a therapeutic radionuclide. While the radionuclidic properties favor its use for several therapeutic applications, the potential for large scale production of 177Lu is also an important aspect for its acceptability as a therapeutic radionuclide. This introductory discussion also summarizes some developing clinical uses and suggested future directions for applications of 177Lu.
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Cite this article as:
Pillai M.R. Ambikalmajan and (Russ) Knapp F. Furn, Evolving Important Role of Lutetium-177 for Therapeutic Nuclear Medicine, Current Radiopharmaceuticals 2015; 8 (2) . https://dx.doi.org/10.2174/1874471008666150312155959
DOI https://dx.doi.org/10.2174/1874471008666150312155959 |
Print ISSN 1874-4710 |
Publisher Name Bentham Science Publisher |
Online ISSN 1874-4729 |
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