Abstract
In the modern era, humankind is making daily progress through industrialization. As various types of diseases are prevailing worldwide, scientists are using many approaches to manage these diseases, such as gene therapy. A nanoparticle (NP)-based approach is an example of a modern method used to address several pathologies. This modern therapeutic approach aims not only at safely transferring the drug of choice to the site of interest in a biological system but also at ensuring the biocompatibility of these NPs. Hence, various coating methodologies are being employed to avoid NP toxicity as well as immunoreactivity. This short review covers the latest approaches and advances in this biomedical field. Among nanomaterials, gold NPs (GNPs) are comprehensively employed as a diagnostic tool for the treatment and management of diseases such as cancer.
Keywords: Cancer, diseases, gene therapy, gold nanoparticles, health, nanoparticles.
Current Drug Metabolism
Title:Nanoparticle-Based Therapy in Genomics
Volume: 16 Issue: 5
Author(s): Mahmood Rasool, Arif Malik, Abdul Manan, Shakeel Ahmed Ansari, Muhammad Imran Naseer, Mahmood Husain Qazi, Muhammad Asif, Siew Hua Gan and Mohammad Amjad Kamal
Affiliation:
Keywords: Cancer, diseases, gene therapy, gold nanoparticles, health, nanoparticles.
Abstract: In the modern era, humankind is making daily progress through industrialization. As various types of diseases are prevailing worldwide, scientists are using many approaches to manage these diseases, such as gene therapy. A nanoparticle (NP)-based approach is an example of a modern method used to address several pathologies. This modern therapeutic approach aims not only at safely transferring the drug of choice to the site of interest in a biological system but also at ensuring the biocompatibility of these NPs. Hence, various coating methodologies are being employed to avoid NP toxicity as well as immunoreactivity. This short review covers the latest approaches and advances in this biomedical field. Among nanomaterials, gold NPs (GNPs) are comprehensively employed as a diagnostic tool for the treatment and management of diseases such as cancer.
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Cite this article as:
Rasool Mahmood, Malik Arif, Manan Abdul, Ahmed Ansari Shakeel, Imran Naseer Muhammad, Husain Qazi Mahmood, Asif Muhammad, Hua Gan Siew and Amjad Kamal Mohammad, Nanoparticle-Based Therapy in Genomics, Current Drug Metabolism 2015; 16 (5) . https://dx.doi.org/10.2174/1389200216666141208152121
DOI https://dx.doi.org/10.2174/1389200216666141208152121 |
Print ISSN 1389-2002 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5453 |
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