Abstract
An efficient synthesis of 2-substituted benzoxazoles via copper acetate monohydrate oxidative coupling of aldehydes with o-aminophenol is described. This synthetic strategy has some advantages as simple procedure, inexpensive and easily available catalyst, and facile isolation of the products in moderate to good yields.
Keywords: Benzoxazoles, aromatic aldehydes, o-aminophenol, copper acetate monohydrate, oxidative cyclization.
Letters in Organic Chemistry
Title:One-pot Synthesis of 2-Substituted Benzoxazoles Promoted by Copper Acetate Monohydrate
Volume: 11 Issue: 3
Author(s): Guo-Feng Chen, Hai-Dong Shen, Li-Yan Zhang, Hong-Yang Li, Rui-Jia Lan, Bao-Hua Chen, Ji-Tai Li and Qing-Hui Hu
Affiliation:
Keywords: Benzoxazoles, aromatic aldehydes, o-aminophenol, copper acetate monohydrate, oxidative cyclization.
Abstract: An efficient synthesis of 2-substituted benzoxazoles via copper acetate monohydrate oxidative coupling of aldehydes with o-aminophenol is described. This synthetic strategy has some advantages as simple procedure, inexpensive and easily available catalyst, and facile isolation of the products in moderate to good yields.
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Cite this article as:
Chen Guo-Feng, Shen Hai-Dong, Zhang Li-Yan, Li Hong-Yang, Lan Rui-Jia, Chen Bao-Hua, Li Ji-Tai and Hu Qing-Hui, One-pot Synthesis of 2-Substituted Benzoxazoles Promoted by Copper Acetate Monohydrate, Letters in Organic Chemistry 2014; 11 (3) . https://dx.doi.org/10.2174/15701786113106660070
DOI https://dx.doi.org/10.2174/15701786113106660070 |
Print ISSN 1570-1786 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6255 |
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