Abstract
Nutrient perception in the gut is important for the maintenance of nutrient and energy balance in the body. Recently, nutrient perception has attracted the attention of medical researchers, as it may provide an opportunity to prevent obesity and associated disease. Recent progress in functional MRI (fMRI) techniques have enabled noninvasive investigation of whole brain function during the processing of information regarding ingested nutrients from the gut depending on the feeding status in both rodents and human subjects. However, the fMRI technique still has substantial problems because it relies on blood oxygenation levels. Here, a novel fMRI technique is introduced that solves this problem for rodent fMRI studies and fMRI studies of the gut-brain axis.
Keywords: Functional MRI, chemoreception, gastrointestinal tract, vagus nerve, gut hormone.
Current Pharmaceutical Design
Title:Neuroimaging of Gut Nutrient Perception
Volume: 20 Issue: 16
Author(s): Tomokazu Tsurugizawa
Affiliation:
Keywords: Functional MRI, chemoreception, gastrointestinal tract, vagus nerve, gut hormone.
Abstract: Nutrient perception in the gut is important for the maintenance of nutrient and energy balance in the body. Recently, nutrient perception has attracted the attention of medical researchers, as it may provide an opportunity to prevent obesity and associated disease. Recent progress in functional MRI (fMRI) techniques have enabled noninvasive investigation of whole brain function during the processing of information regarding ingested nutrients from the gut depending on the feeding status in both rodents and human subjects. However, the fMRI technique still has substantial problems because it relies on blood oxygenation levels. Here, a novel fMRI technique is introduced that solves this problem for rodent fMRI studies and fMRI studies of the gut-brain axis.
Export Options
About this article
Cite this article as:
Tsurugizawa Tomokazu, Neuroimaging of Gut Nutrient Perception, Current Pharmaceutical Design 2014; 20 (16) . https://dx.doi.org/10.2174/13816128113199990580
DOI https://dx.doi.org/10.2174/13816128113199990580 |
Print ISSN 1381-6128 |
Publisher Name Bentham Science Publisher |
Online ISSN 1873-4286 |
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
- Announcements
Related Articles
-
Cyclooxygenase-2 in Synaptic Signaling
Current Pharmaceutical Design Recombinant Expression, Functional Characterization of Two Scorpion Venom Toxins with Three Disulfide Bridges from the Chinese Scorpion Buthus martensii Karsch
Protein & Peptide Letters Thalamocortical Oscillations: Local Control of EEG Slow Waves
Current Topics in Medicinal Chemistry Neuroprotective Effects of Low-dose Lithium in Individuals at Ultra-high Risk for Psychosis. A Longitudinal MRI/MRS Study
Current Pharmaceutical Design Patent Selections
Recent Patents on CNS Drug Discovery (Discontinued) Computational Methods Dedicated to Neurological Disorder Detection through Epistasis Analysis: A Review
Current Chinese Engineering Science 5-HT3 Receptors: A Potential Therapeutic Target for Epilepsy
Current Neuropharmacology Genome-wide Membrane Protein Structure Prediction
Current Genomics Advances in Synthesis and Medicinal Applications of Compounds Derived from Phthalimide
Current Organic Synthesis Efficient High-throughput Techniques for the Analysis of Disease- Resistant Plant Varieties and Detection of Food Adulteration
Current Protein & Peptide Science Patent Selections
Recent Patents on CNS Drug Discovery (Discontinued) Hematologic Abnormalities in the Antiphospholipid Syndrome
Current Rheumatology Reviews Golgi Localization of Glycosyltransferases Involved in Ganglioside Biosynthesis
Current Drug Targets Clinical Uses of Melatonin in Neurological Diseases and Mental and Behavioural Disorders
Current Medicinal Chemistry Applications of Nuclear Technique to Biological Sciences Labelled Compounds, Radioactive Tracers, and X-Ray Tomography
Current Topics in Medicinal Chemistry Medications Acting on the GABA System in the Treatment of Alcoholic Patients
Current Pharmaceutical Design Low-Dose Mercury Exposure in Early Life: Relevance of Thimerosal to Fetuses, Newborns and Infants
Current Medicinal Chemistry The Neuropharmacological Preclinical Effects of <i>Nigella sativa</i>: A Review
Current Bioactive Compounds Histamine H3 Receptor Function and Ligands: Recent Developments
Mini-Reviews in Medicinal Chemistry Increased Epileptiform EEG Activity and Decreased Seizure Threshold in Arctic APP Transgenic Mouse Model of Alzheimer’s Disease
Current Alzheimer Research