Abstract
This review discusses the biological and medicinal significance of one of the most important and interesting heterocyclic ring systems, the pyrimidine and its condensed derivatives. Herein, various physiologically important molecules, as well as, therapeutically used drugs having a pyrimidine or condensed pyrimidine system in their chemical structures, have been covered. The chemistry and synthesis of pyrimidines have also been briefly discussed.
Keywords: Bioactive Heterocycles, Pyrimidines, Condensed Pyrimidines, Biological significance, Medicinal significance, Synthesis.
Graphical Abstract
Current Topics in Medicinal Chemistry
Title:The Chemistry and Bio-Medicinal Significance of Pyrimidines & Condensed Pyrimidines
Volume: 16 Issue: 28
Author(s): K. S. Jain, N. Arya, N. N. Inamdar, P. B. Auti, S. A. Unawane, H. H. Puranik, M. S. Sanap, A. D. Inamke, V. J. Mahale, C. S. Prajapati and C. J. Shishoo
Affiliation:
Keywords: Bioactive Heterocycles, Pyrimidines, Condensed Pyrimidines, Biological significance, Medicinal significance, Synthesis.
Abstract: This review discusses the biological and medicinal significance of one of the most important and interesting heterocyclic ring systems, the pyrimidine and its condensed derivatives. Herein, various physiologically important molecules, as well as, therapeutically used drugs having a pyrimidine or condensed pyrimidine system in their chemical structures, have been covered. The chemistry and synthesis of pyrimidines have also been briefly discussed.
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Jain S. K., Arya N., Inamdar N. N., Auti B. P., Unawane A. S., Puranik H. H., Sanap S. M., Inamke D. A., Mahale J. V., Prajapati S. C. and Shishoo J. C., The Chemistry and Bio-Medicinal Significance of Pyrimidines & Condensed Pyrimidines, Current Topics in Medicinal Chemistry 2016; 16 (28) . https://dx.doi.org/10.2174/1568026616666160609100410
DOI https://dx.doi.org/10.2174/1568026616666160609100410 |
Print ISSN 1568-0266 |
Publisher Name Bentham Science Publisher |
Online ISSN 1873-4294 |
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