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Combinatorial Chemistry & High Throughput Screening

Editor-in-Chief

ISSN (Print): 1386-2073
ISSN (Online): 1875-5402

A Study on Factors Affecting the Reproducibility of a Chemical Tongue Analysis Responding to Amino Acids

Author(s): Laurent A. Baumes and Jose Ranilla

Volume 16, Issue 7, 2013

Page: [572 - 583] Pages: 12

DOI: 10.2174/1386207311316070007

Price: $65

Abstract

Four fluorescent tricyclic basic dyes with two hollow organic capsules namely cucurbit[n]urils (CB[n]), n = 7 and 8, compose the chemical tongue that is examined for α-amino acids recognition. This array is able to identify and discriminate 18 α-amino acids up to 10-4 M without the need of enzyme activation. The paper shows the importance of the classification technique employed in order to reach the highest recognition rate at this concentration.

Keywords: Amino acids, chemical tongue, classification, clustering, colorimetric, machine learning, statistics.

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