Sydnones: A Brief Review

Roshini      Chandrasekhar; M.J.      Nanjan

doi:10.2174/13895575112091359

Abstract

Sydnones are mesoionic heterocyclic aromatic compounds. They have been widely studied for some important biological activities like antiviral, antitumor, antimicrobial, anti-inflammatory, anticancer, analgesic, anthelmintic and antihypertensive activities. The aim of the present article is to review the available information on sydnones and the derivatives of sydnones and also a look at the future perspectives.

Keywords: Sydnone, mesoionic, oxadiazolium, prototropy, in vacuo, TFAA, N-dimethylchlorosulfitemethaniniumchloride, in vitro, bis-sydnones, pyrrolidino, in vivo