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Current Drug Safety

Editor-in-Chief

ISSN (Print): 1574-8863
ISSN (Online): 2212-3911

Oxaliplatin-Induced Lung Toxicity. Case Report and Review of the Literature

Author(s): Tiziana Prochilo, Chiara Abeni, Paola Bertocchi and Alberto Zaniboni

Volume 7, Issue 2, 2012

Page: [179 - 182] Pages: 4

DOI: 10.2174/157488612802715672

Price: $65

Abstract

Rapidly developing pulmonary fibrosis associated with the use of the anti-cancer drug oxaliplatin has been reported mainly by Asiatic literature as isolate case reports. This rare but potentially fatal side effect has neither identified risk factors nor established treatment guideline. We report here a new clinical case concerning a patient with advanced gastric cancer treated with the oxaliplatin-based FOLFOX regimen along with a review of the literature as well as a discussion of emerging experimental treatment mainly based on imatinib.

Keywords: Imatinib, oxaliplatin, pulmonary fibrosis.


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