Review Article

子痫前期的治疗前景-简评

卷 26, 期 25, 2019

页: [4786 - 4798] 页: 13

弟呕挨: 10.2174/0929867326666190228115423

价格: $65

摘要

背景:癫痫前期(PE)的特征是早发症状,例如孕妇血压升高,蛋白尿和水肿,并可能导致患病女性的癫痫发作。 目前,尚无可用于治疗这种疾病的治疗药物,但是有干预措施可根据胎儿的妊娠期来调节症状,尽管最受青睐的选择是胎儿和胎盘的分娩。 目的:寻找与PE相关的生物分子,以鉴定诊断标记和治疗线索。 结果:通过文献检索,鉴定了与PE相关的生物分子,例如Corin和胎盘蛋白13(PP13)。 因此,可以深入了解PE病因中涉及的各种机制途径。 然而,也很明显,PE不能仅归因于任何单一机制,而是由于导致该疾病状况发展的不同因素的相互作用。 结论:确定的生物标志物最终将有助于了解这种复杂疾病,并可能导致发现潜在的有效分子靶标用于临床试验,从而为受影响的孕妇提供有价值的治疗选择。

关键词: 子痫前期,高血压,生物标志物,corin,胎盘蛋白13,腺苷

[1]
Roberts, J.M. Preeclampsia: what we know and what we do not know. Semin. Perinatol., 2000, 24(1), 24-28.
[http://dx.doi.org/10.1016/S0146-0005(00)80050-6] [PMID: 10709854]
[2]
Saleh, A.A.; Bottoms, S.F.; Welch, R.A.; Ali, A.M.; Mariona, F.G.; Mammen, E.F. Preeclampsia, delivery, and the hemostatic system. Am. J. Obstet. Gynecol., 1987, 157(2), 331-336.
[http://dx.doi.org/10.1016/S0002-9378(87)80163-1] [PMID: 2441602]
[3]
Roberts, J.M.; Taylor, R.N.; Musci, T.J.; Rodgers, G.M.; Hubel, C.A.; McLaughlin, M.K. Preeclampsia: an endothelial cell disorder. Am. J. Obstet. Gynecol., 1990, 32(3), 1200-1204.
[4]
Sibai, B.; Dekker, G.; Kupferminc, M. Pre-eclampsia. Lancet, 2005, 365(9461), 785-799.
[http://dx.doi.org/10.1016/S0140-6736(05)17987-2] [PMID: 15733721]
[5]
Tomimatsu, T.; Mimura, K.; Endo, M.; Kumasawa, K.; Kimura, T. Pathophysiology of preeclampsia: an angiogenic imbalance and long-lasting systemic vascular dysfunction. Hypertens. Res., 2017, 40(4), 305-310.
[http://dx.doi.org/10.1038/hr.2016.152] [PMID: 27829661]
[6]
Chen, C.W.; Jaffe, I.Z.; Karumanchi, S.A. Pre-eclampsia and cardiovascular disease. Cardiovasc. Res., 2014, 101(4), 579-586.
[http://dx.doi.org/10.1093/cvr/cvu018] [PMID: 24532051]
[7]
Ness, R.B.; Sibai, B.M. Shared and disparate components of the pathophysiologies of fetal growth restriction and preeclampsia. Am. J. Obstet. Gynecol., 2006, 195(1), 40-49.
[http://dx.doi.org/10.1016/j.ajog.2005.07.049] [PMID: 16813742]
[8]
Odegård, R.A.; Vatten, L.J.; Nilsen, S.T.; Salvesen, K.A.; Austgulen, R. Preeclampsia and fetal growth. Obstet. Gynecol., 2000, 96(6), 950-955.
[PMID: 11084184]
[9]
Dhariwal, N.K.; Lynde, G.C. Update in the Management of Patients with Preeclampsia. Anesthesiol. Clin., 2017, 35(1), 95-106.
[http://dx.doi.org/10.1016/j.anclin.2016.09.009] [PMID: 28131123]
[10]
Hofmeyr, R.; Matjila, M.; Dyer, R. Preeclampsia in 2017: obstetric and anaesthesia management. Best Pract. Res. Clin. Anaesthesiol., 2017, 31(1), 125-138.
[http://dx.doi.org/10.1016/j.bpa.2016.12.002] [PMID: 28625300]
[11]
Genbacev, O.; Zhou, Y.; Ludlow, J.W.; Fisher, S.J. Regulation of human placental development by oxygen tension. Science, 1997, 277(5332), 1669-1672.
[http://dx.doi.org/10.1126/science.277.5332.1669] [PMID: 9287221]
[12]
Huppertz, B. The anatomy of the normal placenta. J. Clin. Pathol., 2008, 61(12), 1296-1302.
[http://dx.doi.org/10.1136/jcp.2008.055277] [PMID: 18755720]
[13]
Nagar, T.; Sharma, D.; Choudhary, M.; Khoiwal, S.; Nagar, R.P.; Pandita, A. The Role of Uterine and Umbilical Arterial Doppler in High-risk Pregnancy: A Prospective Observational Study from India. Clin. Med. Insights Reprod. Health, 2015, 9, 1-5.
[http://dx.doi.org/10.4137/CMRH.S24048] [PMID: 25922590]
[14]
Baschat, A.A.; Galan, H.L.; Bhide, A.; Berg, C.; Kush, M.L.; Oepkes, D.; Thilaganathan, B.; Gembruch, U.; Harman, C.R. Doppler and biophysical assessment in growth restricted fetuses: distribution of test results. Ultrasound Obstet. Gynecol., 2006, 27(1), 41-47.
[http://dx.doi.org/10.1002/uog.2657] [PMID: 16323151]
[15]
Oyston, C.J.; Stanley, J.L.; Baker, P.N. Potential targets for the treatment of preeclampsia. Expert Opin. Ther. Targets, 2015, 19(11), 1517-1530.
[http://dx.doi.org/10.1517/14728222.2015.1088004] [PMID: 26389556]
[16]
Saito, S.; Sakai, M.; Sasaki, Y.; Nakashima, A.; Shiozaki, A. Inadequate tolerance induction may induce pre-eclampsia. J. Reprod. Immunol., 2007, 76(1-2), 30-39.
[http://dx.doi.org/10.1016/j.jri.2007.08.002] [PMID: 17935792]
[17]
Robillard, P-Y.; Dekker, G.; Chaouat, G.; Hulsey, T.C.; Saftlas, A. Epidemiological studies on primipaternity and immunology in preeclampsia--a statement after twelve years of workshops. J. Reprod. Immunol., 2011, 89(2), 104-117.
[http://dx.doi.org/10.1016/j.jri.2011.02.003] [PMID: 21543120]
[18]
Feeney, J.G.; Scott, J.S. Pre-eclampsia and changed paternity. Eur. J. Obstet. Gynecol. Reprod. Biol., 1980, 11(1), 35-38.
[http://dx.doi.org/10.1016/0028-2243(80)90051-9] [PMID: 7193608]
[19]
Rowe, J.H.; Ertelt, J.M.; Xin, L.; Way, S.S. Pregnancy imprints regulatory memory that sustains anergy to fetal antigen. Nature, 2012, 490(7418), 102-106.
[http://dx.doi.org/10.1038/nature11462] [PMID: 23023128]
[20]
Robertson, S.A.; Guerin, L.R.; Bromfield, J.J.; Branson, K.M.; Ahlström, A.C.; Care, A.S. Seminal fluid drives expansion of the CD4+CD25+ T regulatory cell pool and induces tolerance to paternal alloantigens in mice. Biol. Reprod., 2009, 80(5), 1036-1045.
[http://dx.doi.org/10.1095/biolreprod.108.074658] [PMID: 19164169]
[21]
Robertson, S.A.; Guerin, L.R.; Moldenhauer, L.M.; Hayball, J.D. Activating T regulatory cells for tolerance in early pregnancy - the contribution of seminal fluid. J. Reprod. Immunol., 2009, 83(1-2), 109-116.
[http://dx.doi.org/10.1016/j.jri.2009.08.003] [PMID: 19875178]
[22]
Shima, T.; Inada, K.; Nakashima, A.; Ushijima, A.; Ito, M.; Yoshino, O.; Saito, S. Paternal antigen-specific proliferating regulatory T cells are increased in uterine-draining lymph nodes just before implantation and in pregnant uterus just after implantation by seminal plasma-priming in allogeneic mouse pregnancy. J. Reprod. Immunol., 2015, 108, 72-82.
[http://dx.doi.org/10.1016/j.jri.2015.02.005] [PMID: 25817463]
[23]
Aluvihare, V.R.; Kallikourdis, M.; Betz, A.G.; Regulatory, T. Regulatory T cells mediate maternal tolerance to the fetus. Nat. Immunol., 2004, 5(3), 266-271.
[http://dx.doi.org/10.1038/ni1037] [PMID: 14758358]
[24]
Sasaki, Y.; Darmochwal-Kolarz, D.; Suzuki, D.; Sakai, M.; Ito, M.; Shima, T.; Shiozaki, A.; Rolinski, J.; Saito, S. Proportion of peripheral blood and decidual CD4(+) CD25(bright) regulatory T cells in pre-eclampsia. Clin. Exp. Immunol., 2007, 149(1), 139-145.
[http://dx.doi.org/10.1111/j.1365-2249.2007.03397.x] [PMID: 17459078]
[25]
Rahimzadeh, M.; Norouzian, M.; Arabpour, F.; Naderi, N. Regulatory T-cells and preeclampsia: an overview of literature. Expert Rev. Clin. Immunol., 2016, 12(2), 209-227.
[http://dx.doi.org/10.1586/1744666X.2016.1105740] [PMID: 26580672]
[26]
Dekker, G.; Robillard, P.Y.; Roberts, C. The etiology of preeclampsia: the role of the father. J. Reprod. Immunol., 2011, 89(2), 126-132.
[http://dx.doi.org/10.1016/j.jri.2010.12.010] [PMID: 21529966]
[27]
Kanagalingam, M.G.; Forouhi, N.G.; Greer, I.A.; Sattar, N. Changes in booking body mass index over a decade: retrospective analysis from a Glasgow Maternity Hospital. BJOG, 2005, 112(10), 1431-1433.
[http://dx.doi.org/10.1111/j.1471-0528.2005.00685.x] [PMID: 16167951]
[28]
Salihu, H.M.; De La Cruz, C.; Rahman, S.; August, E.M. Does maternal obesity cause preeclampsia? A systematic review of the evidence. Minerva Ginecol., 2012, 64(4), 259-280.
[PMID: 22728572]
[29]
Rosenberg, T.J.; Garbers, S.; Lipkind, H.; Chiasson, M.A. Maternal obesity and diabetes as risk factors for adverse pregnancy outcomes: differences among 4 racial/ethnic groups. Am. J. Public Health, 2005, 95(9), 1545-1551.
[http://dx.doi.org/10.2105/AJPH.2005.065680] [PMID: 16118366]
[30]
Molvarec, A.; Shiozaki, A.; Ito, M.; Toldi, G.; Stenczer, B.; Szarka, A.; Nakashima, A.; Vásárhelyi, B.; Rigó, J., Jr; Saito, S. Increased prevalence of peripheral blood granulysin-producing cytotoxic T lymphocytes in preeclampsia. J. Reprod. Immunol., 2011, 91(1-2), 56-63.
[http://dx.doi.org/10.1016/j.jri.2011.03.012] [PMID: 21763002]
[31]
Jolly, M.C.; Sebire, N.J.; Harris, J.P.; Regan, L.; Robinson, S. Risk factors for macrosomia and its clinical consequences: a study of 350,311 pregnancies. Eur. J. Obstet. Gynecol. Reprod. Biol., 2003, 111(1), 9-14.
[http://dx.doi.org/10.1016/S0301-2115(03)00154-4] [PMID: 14557004]
[32]
Gilbert, J.S.; Ryan, M.J.; LaMarca, B.B.; Sedeek, M.; Murphy, S.R.; Granger, J.P. Pathophysiology of hypertension during preeclampsia: linking placental ischemia with endothelial dysfunction. Am. J. Physiol. Heart Circ. Physiol., 2008, 294, 541-550.
[http://dx.doi.org/10.1152/ajpheart.01113.2007]
[33]
Poston, L. Endothelial dysfunction in pre-eclampsia. Pharmacol. Rep., 2006, 58(Suppl.), 69-74.
[PMID: 17332674]
[34]
Roberts, J.M.; Taylor, R.N.; Goldfien, A. Clinical and biochemical evidence of endothelial cell dysfunction in the pregnancy syndrome preeclampsia. Am. J. Hypertens., 1991, 4(8), 700-708.
[http://dx.doi.org/10.1093/ajh/4.8.700] [PMID: 1930853]
[35]
McCarthy, J.F.; Misra, D.N.; Roberts, J.M. Maternal plasma leptin is increased in preeclampsia and positively correlates with fetal cord concentration. Am. J. Obstet. Gynecol., 1999, 180(3 Pt 1), 731-736.
[http://dx.doi.org/10.1016/S0002-9378(99)70280-2] [PMID: 10076155]
[36]
Meekins, J.W. Interleukin-6, tumour necrosis factor and soluble tumour necrosis factor receptors in women with pre-eclampsia. Br. J. Obstet. Gynaecol., 1995, 102(10), 842-843.
[http://dx.doi.org/10.1111/j.1471-0528.1995.tb10859.x] [PMID: 7547749]
[37]
Santangeli, L.; Sattar, N.; Huda, S.S. Impact of maternal obesity on perinatal and childhood outcomes. Best Pract. Res. Clin. Obstet. Gynaecol., 2015, 29(3), 438-448.
[http://dx.doi.org/10.1016/j.bpobgyn.2014.10.009] [PMID: 25497183]
[38]
Sibai, B.M. Risk factors, pregnancy complications, and prevention of hypertensive disorders in women with pregravid diabetes mellitus. J. Matern. Fetal Med., 2000, 9(1), 62-65.
[http://dx.doi.org/10.1002/(SICI)1520-6661(200001/02)9:1<62:AID-MFM13>3.0.CO;2-6] [PMID: 10757438]
[39]
Zhe, C.; Ni, Y. Women’s Experiences of Preeclampsia in Pregnancy.. Student Thesis, Lishui University: China,, 2018.www.divaportal.org/smash/get/diva2:1222408/FULLTEXT01.pdf
[40]
Dhyani; Mahantashetti, N. S.; Ganachari, M.; Kambar, S.; Ghatnatti, V. Awareness of gestational diabetes mellitus among pregnant women attending a tertiary health center. Indian J. Heal. Sci. Biomed. Res., 2018, 11(1), 51-55.
[http://dx.doi.org/10.4103/kleuhsj.kleuhsj_130_17]
[41]
Wilkinson, J.; Cole, G. Preeclampsia knowledge among women in Utah. Hypertens. Pregnancy, 2018, 37(1), 18-24.
[http://dx.doi.org/10.1080/10641955.2017.1397691] [PMID: 29140734]
[42]
Cox, L.S.; Redman, C. The role of cellular senescence in ageing of the placenta. Placenta, 2017, 52, 139-145.
[http://dx.doi.org/10.1016/j.placenta.2017.01.116] [PMID: 28131318]
[43]
Brosens, J.J.; Parker, M.G.; McIndoe, A.; Pijnenborg, R.; Brosens, I.A. A role for menstruation in preconditioning the uterus for successful pregnancy. Am. J. Obstet. Gynecol., 2009, 200(6), 615.e1-615.e6.
[http://dx.doi.org/10.1016/j.ajog.2008.11.037] [PMID: 19136085]
[44]
Kassebaum, N.J.; Bertozzi-Villa, A.; Coggeshall, M.S.; Shackelford, K.A.; Steiner, C.; Heuton, K.R.; Gonzalez-Medina, D.; Barber, R.; Huynh, C.; Dicker, D.; Templin, T.; Wolock, T.M.; Ozgoren, A.A.; Abd-Allah, F.; Abera, S.F.; Abubakar, I.; Achoki, T.; Adelekan, A.; Ademi, Z.; Adou, A.K.; Adsuar, J.C.; Agardh, E.E.; Akena, D.; Alasfoor, D.; Alemu, Z.A.; Alfonso-Cristancho, R.; Alhabib, S.; Ali, R.; Al Kahbouri, M.J.; Alla, F.; Allen, P.J.; AlMazroa, M.A.; Alsharif, U.; Alvarez, E.; Alvis-Guzmán, N.; Amankwaa, A.A.; Amare, A.T.; Amini, H.; Ammar, W.; Antonio, C.A.; Anwari, P.; Arnlöv, J.; Arsenijevic, V.S.; Artaman, A.; Asad, M.M.; Asghar, R.J.; Assadi, R.; Atkins, L.S.; Badawi, A.; Balakrishnan, K.; Basu, A.; Basu, S.; Beardsley, J.; Bedi, N.; Bekele, T.; Bell, M.L.; Bernabe, E.; Beyene, T.J.; Bhutta, Z.; Bin Abdulhak, A.; Blore, J.D.; Basara, B.B.; Bose, D.; Breitborde, N.; Cárdenas, R.; Castañeda-Orjuela, C.A.; Castro, R.E.; Catalá-López, F.; Cavlin, A.; Chang, J.C.; Che, X.; Christophi, C.A.; Chugh, S.S.; Cirillo, M.; Colquhoun, S.M.; Cooper, L.T.; Cooper, C.; da Costa Leite, I.; Dandona, L.; Dandona, R.; Davis, A.; Dayama, A.; Degenhardt, L.; De Leo, D.; del Pozo-Cruz, B.; Deribe, K.; Dessalegn, M.; deVeber, G.A.; Dharmaratne, S.D.; Dilmen, U.; Ding, E.L.; Dorrington, R.E.; Driscoll, T.R.; Ermakov, S.P.; Esteghamati, A.; Faraon, E.J.; Farzadfar, F.; Felicio, M.M.; Fereshtehnejad, S.M.; de Lima, G.M.; Forouzanfar, M.H.; França, E.B.; Gaffikin, L.; Gambashidze, K.; Gankpé, F.G.; Garcia, A.C.; Geleijnse, J.M.; Gibney, K.B.; Giroud, M.; Glaser, E.L.; Goginashvili, K.; Gona, P.; González-Castell, D.; Goto, A.; Gouda, H.N.; Gugnani, H.C.; Gupta, R.; Gupta, R.; Hafezi-Nejad, N.; Hamadeh, R.R.; Hammami, M.; Hankey, G.J.; Harb, H.L.; Havmoeller, R.; Hay, S.I.; Pi, I.B.; Hoek, H.W.; Hosgood, H.D.; Hoy, D.G.; Husseini, A.; Idrisov, B.T.; Innos, K.; Inoue, M.; Jacobsen, K.H.; Jahangir, E.; Jee, S.H.; Jensen, P.N.; Jha, V.; Jiang, G.; Jonas, J.B.; Juel, K.; Kabagambe, E.K.; Kan, H.; Karam, N.E.; Karch, A.; Karema, C.K.; Kaul, A.; Kawakami, N.; Kazanjan, K.; Kazi, D.S.; Kemp, A.H.; Kengne, A.P.; Kereselidze, M.; Khader, Y.S.; Khalifa, S.E.; Khan, E.A.; Khang, Y.H.; Knibbs, L.; Kokubo, Y.; Kosen, S.; Defo, B.K.; Kulkarni, C.; Kulkarni, V.S.; Kumar, G.A.; Kumar, K.; Kumar, R.B.; Kwan, G.; Lai, T.; Lalloo, R.; Lam, H.; Lansingh, V.C.; Larsson, A.; Lee, J.T.; Leigh, J.; Leinsalu, M.; Leung, R.; Li, X.; Li, Y.; Li, Y.; Liang, J.; Liang, X.; Lim, S.S.; Lin, H.H.; Lipshultz, S.E.; Liu, S.; Liu, Y.; Lloyd, B.K.; London, S.J.; Lotufo, P.A.; Ma, J.; Ma, S.; Machado, V.M.; Mainoo, N.K.; Majdan, M.; Mapoma, C.C.; Marcenes, W.; Marzan, M.B.; Mason-Jones, A.J.; Mehndiratta, M.M.; Mejia-Rodriguez, F.; Memish, Z.A.; Mendoza, W.; Miller, T.R.; Mills, E.J.; Mokdad, A.H.; Mola, G.L.; Monasta, L.; de la Cruz Monis, J.; Hernandez, J.C.; Moore, A.R.; Moradi-Lakeh, M.; Mori, R.; Mueller, U.O.; Mukaigawara, M.; Naheed, A.; Naidoo, K.S.; Nand, D.; Nangia, V.; Nash, D.; Nejjari, C.; Nelson, R.G.; Neupane, S.P.; Newton, C.R.; Ng, M.; Nieuwenhuijsen, M.J.; Nisar, M.I.; Nolte, S.; Norheim, O.F.; Nyakarahuka, L.; Oh, I.H.; Ohkubo, T.; Olusanya, B.O.; Omer, S.B.; Opio, J.N.; Orisakwe, O.E.; Pandian, J.D.; Papachristou, C.; Park, J.H.; Caicedo, A.J.; Patten, S.B.; Paul, V.K.; Pavlin, B.I.; Pearce, N.; Pereira, D.M.; Pesudovs, K.; Petzold, M.; Poenaru, D.; Polanczyk, G.V.; Polinder, S.; Pope, D.; Pourmalek, F.; Qato, D.; Quistberg, D.A.; Rafay, A.; Rahimi, K.; Rahimi-Movaghar, V. ur Rahman, S.; Raju, M.; Rana, S.M.; Refaat, A.; Ronfani, L.; Roy, N.; Pimienta, T.G.; Sahraian, M.A.; Salomon, J.A.; Sampson, U.; Santos, I.S.; Sawhney, M.; Sayinzoga, F.; Schneider, I.J.; Schumacher, A.; Schwebel, D.C.; Seedat, S.; Sepanlou, S.G.; Servan-Mori, E.E.; Shakh-Nazarova, M.; Sheikhbahaei, S.; Shibuya, K.; Shin, H.H.; Shiue, I.; Sigfusdottir, I.D.; Silberberg, D.H.; Silva, A.P.; Singh, J.A.; Skirbekk, V.; Sliwa, K.; Soshnikov, S.S.; Sposato, L.A.; Sreeramareddy, C.T.; Stroumpoulis, K.; Sturua, L.; Sykes, B.L.; Tabb, K.M.; Talongwa, R.T.; Tan, F.; Teixeira, C.M.; Tenkorang, E.Y.; Terkawi, A.S.; Thorne-Lyman, A.L.; Tirschwell, D.L.; Towbin, J.A.; Tran, B.X.; Tsilimbaris, M.; Uchendu, U.S.; Ukwaja, K.N.; Undurraga, E.A.; Uzun, S.B.; Vallely, A.J.; van Gool, C.H.; Vasankari, T.J.; Vavilala, M.S.; Venketasubramanian, N.; Villalpando, S.; Violante, F.S.; Vlassov, V.V.; Vos, T.; Waller, S.; Wang, H.; Wang, L.; Wang, X.; Wang, Y.; Weichenthal, S.; Weiderpass, E.; Weintraub, R.G.; Westerman, R.; Wilkinson, J.D.; Woldeyohannes, S.M.; Wong, J.Q.; Wordofa, M.A.; Xu, G.; Yang, Y.C.; Yano, Y.; Yentur, G.K.; Yip, P.; Yonemoto, N.; Yoon, S.J.; Younis, M.Z.; Yu, C.; Jin, K.Y.; El Sayed Zaki, M.; Zhao, Y.; Zheng, Y.; Zhou, M.; Zhu, J.; Zou, X.N.; Lopez, A.D.; Naghavi, M.; Murray, C.J.; Lozano, R. Global, regional, and national levels and causes of maternal mortality during 1990-2013: a systematic analysis for the Global Burden of Disease Study 2013. Lancet, 2014, 384(9947), 980-1004.
[http://dx.doi.org/10.1016/S0140-6736(14)60696-6] [PMID: 24797575]
[45]
Ghulmiyyah, L.; Sibai, B. Maternal mortality from preeclampsia/eclampsia. Semin. Perinatol., 2012, 36(1), 56-59.
[http://dx.doi.org/10.1053/j.semperi.2011.09.011] [PMID: 22280867]
[46]
Dennis, A.T. Transthoracic echocardiography in obstetric anaesthesia and obstetric critical illness. Int. J. Obstet. Anesth., 2011, 20(2), 160-168.
[http://dx.doi.org/10.1016/j.ijoa.2010.11.007] [PMID: 21315578]
[47]
American College of Obstetricians and Gynecologists. Task Force on Hypertension in Pregnancy. Hypertension in Pregnancy. Obstet. Gynecol., 2013, 122(5), 1122-1131.
[http://dx.doi.org/10.1097/01.AOG.0000437382.03963.88] [PMID: 24150027]
[48]
Wallace, D.H.; Leveno, K.J.; Cunningham, F.G.; Giesecke, A.H.; Shearer, V.E.; Sidawi, J.E. Randomized comparison of general and regional anesthesia for cesarean delivery in pregnancies complicated by severe preeclampsia. Obstet. Gynecol., 1995, 86(2), 193-199.
[http://dx.doi.org/10.1016/0029-7844(95)00139-I] [PMID: 7617349]
[49]
Parthasarathy, S.; Kumar, V.R.H.; Sripriya, R.; Ravishankar, M. Anesthetic management of a patient presenting with eclampsia. Anesth. Essays Res., 2013, 7(3), 307-312.
[http://dx.doi.org/10.4103/0259-1162.123214] [PMID: 25885974]
[50]
Lu, J.F.; Nightingale, C.H. Magnesium Sulfate in Eclamp-sia and Pre-Eclampsia. Clin. Pharmacokinet., 2000, 38(4), 305-314.
[http://dx.doi.org/10.2165/00003088-200038040-00002] [PMID: 10803454]
[51]
Sibai, B.M.; Taslimi, M.; Abdella, T.N.; Brooks, T.F.; Spinnato, J.A.; Anderson, G.D. Maternal and perinatal outcome of conservative management of severe preeclampsia in midtrimester. Am. J. Obstet. Gynecol., 1985, 152(1), 32-37.
[http://dx.doi.org/10.1016/S0002-9378(85)80171-X] [PMID: 3993711]
[52]
Cui, Y.; Wang, W.; Dong, N.; Lou, J.; Srinivasan, D.K.; Cheng, W.; Huang, X.; Liu, M.; Fang, C.; Peng, J.; Chen, S.; Wu, S.; Liu, Z.; Dong, L.; Zhou, Y.; Wu, Q. Role of corin in trophoblast invasion and uterine spiral artery remodelling in pregnancy. Nature, 2012, 484(7393), 246-250.
[http://dx.doi.org/10.1038/nature10897] [PMID: 22437503]
[53]
Yan, W.; Wu, F.; Morser, J.; Wu, Q. Corin, a transmembrane cardiac serine protease, acts as a pro-atrial natriuretic peptide-converting enzyme. Proc. Natl. Acad. Sci. USA, 2000, 97(15), 8525-8529.
[http://dx.doi.org/10.1073/pnas.150149097] [PMID: 10880574]
[54]
Castro, L.C.; Hobel, C.J.; Gornbein, J. Plasma levels of atrial natriuretic peptide in normal and hypertensive pregnancies: a meta-analysis. Am. J. Obstet. Gynecol., 1994, 171(6), 1642-1651.
[http://dx.doi.org/10.1016/0002-9378(94)90416-2] [PMID: 7802082]
[55]
Bouley, R. Corin: a key protein of an adaptive renal mechanism to respond to salt variation? Kidney Int., 2012, 82(1), 7-8.
[http://dx.doi.org/10.1038/ki.2012.123] [PMID: 22699378]
[56]
Zhou, Y.; Wu, Q. Role of corin and atrial natriuretic peptide in preeclampsia. Placenta, 2013, 34(2), 89-94.
[http://dx.doi.org/10.1016/j.placenta.2012.11.016] [PMID: 23211473]
[57]
Dong, N.; Zhou, T.; Zhang, Y.; Liu, M.; Li, H.; Huang, X.; Liu, Z.; Wu, Y.; Fukuda, K.; Qin, J.; Wu, Q. Corin mutations K317E and S472G from preeclamptic patients alter zymogen activation and cell surface targeting.[Corrected]. J. Biol. Chem., 2014, 289(25), 17909-17916.
[http://dx.doi.org/10.1074/jbc.M114.551424] [PMID: 24828501]
[58]
Qi, X.; Jiang, J.; Zhu, M.; Wu, Q. Human corin isoforms with different cytoplasmic tails that alter cell surface targeting. J. Biol. Chem., 2011, 286(23), 20963-20969.
[http://dx.doi.org/10.1074/jbc.M110.217570] [PMID: 21518754]
[59]
Gadde, R. CD, D.; Sheela, S. Placental Protein 13. J. Circ.Biomarkers, 2018, 7184945441878615.
[http://dx.doi.org/10.1177/1849454418786159]
[60]
Kliman, H.J.; Sammar, M.; Grimpel, Y.I.; Lynch, S.K.; Milano, K.M.; Pick, E.; Bejar, J.; Arad, A.; Lee, J.J.; Meiri, H.; Gonen, R. Placental protein 13 and decidual zones of necrosis: an immunologic diversion that may be linked to preeclampsia. Reprod. Sci., 2012, 19(1), 16-30.
[http://dx.doi.org/10.1177/1933719111424445] [PMID: 21989657]
[61]
Chafetz, I.; Kuhnreich, I.; Sammar, M.; Tal, Y.; Gibor, Y.; Meiri, H.; Cuckle, H.; Wolf, M. First-trimester placental protein 13 screening for preeclampsia and intrauterine growth restriction. Am. J. Obstet. Gynecol., 2007, 197(1), 35.e1-35.e7.
[http://dx.doi.org/10.1016/j.ajog.2007.02.025] [PMID: 17618748]
[62]
Sekizawa, A.; Purwosunu, Y.; Yoshimura, S.; Nakamura, M.; Shimizu, H.; Okai, T.; Rizzo, N.; Farina, A. PP13 mRNA expression in trophoblasts from preeclamptic placentas. Reprod. Sci., 2009, 16(4), 408-413.
[http://dx.doi.org/10.1177/1933719108328615] [PMID: 19087972]
[63]
Akolekar, R.; Syngelaki, A.; Beta, J.; Kocylowski, R.; Nicolaides, K.H. Maternal serum placental protein 13 at 11-13 weeks of gestation in preeclampsia. Prenat. Diagn., 2009, 29(12), 1103-1108.
[http://dx.doi.org/10.1002/pd.2375] [PMID: 19777530]
[64]
Shimizu, H.; Sekizawa, A.; Purwosunu, Y.; Nakamura, M.; Farina, A.; Rizzo, N.; Okai, T. PP13 mRNA expression in the cellular component of maternal blood as a marker for preeclampsia. Prenat. Diagn., 2009, 29(13), 1231-1236.
[http://dx.doi.org/10.1002/pd.2380] [PMID: 19813218]
[65]
Yoneyama, Y.; Suzuki, S.; Sawa, R.; Yoneyama, K.; Power, G.G.; Araki, T. Increased plasma adenosine concentrations and the severity of preeclampsia. Obstet. Gynecol., 2002, 100(6), 1266-1270.
[PMID: 12468172]
[66]
Iriyama, T.; Xia, Y. Placental Adenosine Signaling in the Pathophysiology of Preeclampsia. In: Preeclampsia. Comprehensive Gynecology and Obstetrics.Shigeru ; Saito, , Ed.; Springer: Singapore, 2018; pp. 99-112.
[http://dx.doi.org/10.1007/978-981-10-5891-2_6]
[67]
Venkatesha, S.; Toporsian, M.; Lam, C.; Hanai, J.; Mammoto, T.; Kim, Y.M.; Bdolah, Y.; Lim, K-H.; Yuan, H-T.; Libermann, T.A.; Stillman, I.E.; Roberts, D.; D’Amore, P.A.; Epstein, F.H.; Sellke, F.W.; Romero, R.; Sukhatme, V.P.; Letarte, M.; Karumanchi, S.A. Soluble endoglin contributes to the pathogenesis of preeclampsia. Nat. Med., 2006, 12(6), 642-649.
[http://dx.doi.org/10.1038/nm1429] [PMID: 16751767]
[68]
Aksoy, H.; Kumtepe, Y.; Akçay, F.; Yildirim, A.K. Correlation of P-selectin and lipoprotein(a), and other lipid parameters in preeclampsia. Clin. Exp. Med., 2002, 2(1), 39-43.
[http://dx.doi.org/10.1007/s102380200005] [PMID: 12049188]
[69]
Cetin, I.; Cozzi, V.; Pasqualini, F.; Nebuloni, M.; Garlanda, C.; Vago, L.; Pardi, G.; Mantovani, A. Elevated maternal levels of the long pentraxin 3 (PTX3) in preeclampsia and intrauterine growth restriction. Am. J. Obstet. Gynecol., 2006, 194(5), 1347-1353.
[http://dx.doi.org/10.1016/j.ajog.2005.11.018] [PMID: 16647920]
[70]
Grill, S.; Rusterholz, C.; Zanetti-Dällenbach, R.; Tercanli, S.; Holzgreve, W.; Hahn, S.; Lapaire, O. Potential markers of preeclampsia--a review. Reprod. Biol. Endocrinol., 2009, 7(1), 70.
[http://dx.doi.org/10.1186/1477-7827-7-70] [PMID: 19602262]
[71]
McCarthy, F.P.; Ryan, R.M.; Chappell, L.C. Prospective biomarkers in preterm preeclampsia: a review. Pregnancy Hypertens., 2018, 14, 72-78.
[http://dx.doi.org/10.1016/j.preghy.2018.03.010] [PMID: 30527122]
[72]
Tsai, S.; Hardison, N.E.; James, A.H.; Motsinger-Reif, A.A.; Bischoff, S.R.; Thames, B.H.; Piedrahita, J.A. Transcriptional profiling of human placentas from pregnancies complicated by preeclampsia reveals disregulation of sialic acid acetylesterase and immune signalling pathways. Placenta, 2011, 32(2), 175-182.
[http://dx.doi.org/10.1016/j.placenta.2010.11.014] [PMID: 21183218]
[73]
Vadillo-Ortega, F.; Perichart-Perera, O.; Espino, S.; Avila-Vergara, M.A.; Ibarra, I.; Ahued, R.; Godines, M.; Parry, S.; Macones, G.; Strauss, J.F. Effect of supplementation during pregnancy with L-arginine and antioxidant vitamins in medical food on pre-eclampsia in high risk population: randomised controlled trial. BMJ, 2011, 342, d2901.
[http://dx.doi.org/10.1136/bmj.d2901] [PMID: 21596735]
[74]
Chaiworapongsa, T.; Chaemsaithong, P.; Korzeniewski, S.J.; Yeo, L.; Romero, R. Pre-eclampsia part 2: prediction, prevention and management. Nat. Rev. Nephrol., 2014, 10(9), 531-540.
[http://dx.doi.org/10.1038/nrneph.2014.103] [PMID: 25003612]
[75]
Venkatesha, S.; Toporsian, M.; Lam, C.; Hanai, J.; Mammoto, T.; Kim, Y.M.; Bdolah, Y.; Lim, K-H.; Yuan, H-T.; Libermann, T.A.; Stillman, I.E.; Roberts, D.; D’Amore, P.A.; Epstein, F.H.; Sellke, F.W.; Romero, R.; Sukhatme, V.P.; Letarte, M.; Karumanchi, S.A. Soluble endoglin contributes to the pathogenesis of preeclampsia. Nat. Med., 2006, 12(6), 642-649.
[http://dx.doi.org/10.1038/nm1429] [PMID: 16751767]
[76]
Mol, B.W.J.; Roberts, C.T.; Thangaratinam, S.; Magee, L.A.; de Groot, C.J.M.; Hofmeyr, G.J. Pre-eclampsia. Lancet, 2016, 387(10022), 999-1011.
[http://dx.doi.org/10.1016/S0140-6736(15)00070-7] [PMID: 26342729]
[77]
Steinberg, G.; Khankin, E.V.; Karumanchi, S.A. Angiogenic factors and preeclampsia. Thromb. Res., 2009, 123(Suppl. 2), S93-S99.
[http://dx.doi.org/10.1016/S0049-3848(09)70020-9] [PMID: 19217486]
[78]
Kanasaki, K.; Palmsten, K.; Sugimoto, H.; Ahmad, S.; Hamano, Y.; Xie, L.; Parry, S.; Augustin, H.G.; Gattone, V.H.; Folkman, J.; Strauss, J.F.; Kalluri, R. Deficiency in catechol-O-methyltransferase and 2-methoxyoestradiol is associated with pre-eclampsia. Nature, 2008, 453(7198), 1117-1121.
[http://dx.doi.org/10.1038/nature06951] [PMID: 18469803]
[79]
Chaiworapongsa, T.; Chaemsaithong, P.; Yeo, L.; Romero, R. Pre-eclampsia part 1: current understanding of its pathophysiology. Nat. Rev. Nephrol., 2014, 10(8), 466-480.
[http://dx.doi.org/10.1038/nrneph.2014.102] [PMID: 25003615]
[80]
Eskenazi, B.; Fenster, L.; Sidney, S. A multivariate analysis of risk factors for preeclampsia. JAMA, 1991, 266(2), 237-241.
[http://dx.doi.org/10.1001/jama.1991.03470020063033] [PMID: 2056625]
[81]
Conde-Agudelo, A.; Belizán, J.M.; Lindmark, G. Maternal morbidity and mortality associated with multiple gestations. Obstet. Gynecol., 2000, 95(6 Pt 1), 899-904.
[http://dx.doi.org/10.1097/00006250-200006000-00022] [PMID: 10831988]

Rights & Permissions Print Cite
© 2024 Bentham Science Publishers | Privacy Policy