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Review Article

目前关于无机纳米材料在医疗保健领域安全性的亮点

卷 26, 期 12, 2019

页: [2147 - 2165] 页: 19

弟呕挨: 10.2174/0929867325666180723121804

价格: $65

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摘要

近年来，无机材料主要存在于用于保健的产品中。文献给出了许多保健产品中使用的无机材料的许多实例，主要是在制药领域。银，氧化锌，氧化钛，氧化铁，金，介孔二氧化硅，类水滑石化合物和纳米粘土是纳米尺寸形式中用于健康领域的不同应用的最常见的无机材料。通常，这些材料用于实现全身用途的制剂，通常旨在对病理部位进行特异性靶向。当靶位于细胞内空间时，纳米尺寸通常优选用于获得细胞内化。一些材料经常用于局部制剂中作为流变剂，吸附剂，消光剂，物理防晒剂（例如氧化锌，二氧化钛）等。最近的研究强调，使用纳米无机材料可能会带来健康风险。直到几年前，非常小的尺寸（纳米尺度）代表了一个基本要求;然而，它目前负责无机材料的毒性。这个方面非常重要，因为在市场上可获得的许多产品中通常可以找到许多无机材料，通常专用于婴儿和儿童。使用这些材料时不考虑其尺寸特性而增加用户/患者的风险。本综述对目前研究的深入分析进行了深入分析，这些研究记录了纳米无机材料的毒性，特别是那些主要用于市场上可用产品的纳米无机材料。

关键词: 无机物，纳米材料，细胞毒性，皮肤，化妆品，皮肤病产品。

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