摘要
黄酮类化合物是多酚类化合物，已经证实了各种健康益处。这篇综述将阐明黄酮类化合物作为白色念珠菌感染的潜在抗真菌药物。白色念珠菌是一种机会致病菌，由于许多毒力因子增强其致病性而能够引起严重的健康问题。最重要的毒力因子之一是念珠菌形成生物膜的能力，该生物膜对抗真菌药物的治疗具有高度抗性;减少这种病原体更具挑战性。本综述将重点介绍目前有关个体黄酮类化合物的知识，这些化合物具有在体外处理白色念珠菌的潜力，特别关注抗生素膜的潜力，并在可能的情况下深入了解作用方式。用于治疗念珠菌病的大多数商业药物属于唑类，因此将黄酮类化合物的活性与新合成的唑类化合物的活性以及已经作为官方治疗剂已经在市场上使用的唑类药物进行比较。该文献综述将为推动未来研究探索新型合成唑类或进一步检测广泛的天然黄酮类化合物提供利弊。
关键词: 黄酮类，唑类，念珠菌病，念珠菌属，毒力因子，抗真菌药，生物膜。
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