Abstract
2,3-Dichloro-1,4-naphthoquinone is a special naphthoquinone with four electrophilic sites, useful for applications in organic synthesis and preparation of a diverse new compounds, such as 2,3-substituted derivatives and heterocycles, including those with the core naphthoquinone structure fused. It has also been used for the preparation of compounds for evaluation against several biological targets. This review will describe the most recent applications of 2,3-dichloro-1,4-naphthoquinone in organic synthesis.
Keywords: Quinones, synthetic applications, biological activity, heterocycles, cyclization reactions, nucleophilic substitutions, napthoquinone.
Graphical Abstract
Mini-Reviews in Organic Chemistry
Title:2,3-Dichloro-1,4-Naphthoquinone in Organic Synthesis: Recent Advances
Volume: 14 Issue: 5
Author(s): Luana da S. M. Forezi, Mariana F. C. Cardoso, Dora C. S. Costa, Fernando de C. da Silva and Vitor F. Ferreira*
Affiliation:
- Universidade Federal Fluminense, Departamento de Química Orgânica, Programa de Pós- Graduação em Química, Outeiro de São João Baptista, 24020-141 Niterói, RJ,Brazil
Keywords: Quinones, synthetic applications, biological activity, heterocycles, cyclization reactions, nucleophilic substitutions, napthoquinone.
Abstract: 2,3-Dichloro-1,4-naphthoquinone is a special naphthoquinone with four electrophilic sites, useful for applications in organic synthesis and preparation of a diverse new compounds, such as 2,3-substituted derivatives and heterocycles, including those with the core naphthoquinone structure fused. It has also been used for the preparation of compounds for evaluation against several biological targets. This review will describe the most recent applications of 2,3-dichloro-1,4-naphthoquinone in organic synthesis.
Export Options
About this article
Cite this article as:
Forezi da S. M. Luana, Cardoso F. C. Mariana, Costa C. S. Dora , da Silva de C. Fernando and Ferreira F. Vitor *, 2,3-Dichloro-1,4-Naphthoquinone in Organic Synthesis: Recent Advances, Mini-Reviews in Organic Chemistry 2017; 14 (5) . https://dx.doi.org/10.2174/1570193X14666170518125507
DOI https://dx.doi.org/10.2174/1570193X14666170518125507 |
Print ISSN 1570-193X |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6298 |
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
Related Articles
-
Small and Long Non-Coding RNAs: Novel Targets in Perspective Cancer Therapy
Current Genomics Accuracy of a Topical PET/CT Scanner on SUV Measurements of Small Volumes SUV
Current Medical Imaging Lumiflavin Enhances the Effects of Ionising Radiation on Ovarian Cancer Stem-Like Cells by Inhibiting Autophagy
Anti-Cancer Agents in Medicinal Chemistry Drug Therapy of Neuropathic Pain: Current Developments and Future Perspectives
Current Drug Targets Novel Inhibitors of Inosine Monophosphate Dehydrogenase in Patent Literature of the Last Decade
Recent Patents on Anti-Cancer Drug Discovery Pharmacological Properties of Indazole Derivatives: Recent Developments
Mini-Reviews in Medicinal Chemistry PI3K Pathway Inhibitors: Better Not Left Alone
Current Pharmaceutical Design Manipulation of Glycolysis in Malignant Tumors: Fantasy or Therapy?
Current Medicinal Chemistry The High Mobility Group A1 (HMGA1) Transcriptome in Cancer and Development
Current Molecular Medicine Recent Advances in Radiation Therapy of Cancer Cells: A Step towards an Experimental and Systems Biology Framework
Current Radiopharmaceuticals Connective Tissue Remodeling: Cross-Talk between Endothelins and Matrix Metalloproteinases
Current Vascular Pharmacology Non-Camptothecin DNA Topoisomerase I Inhibitors in Cancer Therapy
Current Topics in Medicinal Chemistry Current Constructs and Targets in Clinical Development for Antibody- Based Cancer Therapy
Current Drug Targets Receptor Tyrosine Kinases as Therapeutic Targets the Model of the MET Oncogene
Current Drug Targets Beneficial Effect of Peptides from Microalgae on Anticancer
Current Protein & Peptide Science Plasmid-Mediated Muscle-Targeted Gene Therapy for Circulating Therapeutic Protein Replacement: A Tale of the Tortoise and the Hare?
Current Gene Therapy Mesenchymal Stem Cells for Anti-Cancer Drug Delivery
Recent Patents on Anti-Cancer Drug Discovery Curcumin and its Formulations: Potential Anti-Cancer Agents
Anti-Cancer Agents in Medicinal Chemistry Cancer Pharmacogenomics: Germline DNA, Tumor DNA, or Both?
Current Pharmacogenomics Pyruvate Kinase M2: Regulatory Circuits and Potential for Therapeutic Intervention
Current Pharmaceutical Design