Abstract
This article considered already existing studies about Deep Brain Stimulation in Mood and Anxiety Disorders. In particular, articles regarding Obsessive-Compulsive Disorder and Major Depression were mostly analyzed, due to the lack of researches about other types of Mood and Anxiety Disorders. We have concentrated on the target areas where Deep Brain Stimulation was most commonly applied, and on the effects this measure had on treatment-refractory patients. The obtained results showed that the stimulation of the: nucleus accumbens, subgenual cingulate cortex and ventral capsule/ventral striatum, has a positive influence on the development of the disorders investigated, sometimes showing the complete remission of the symptoms. Although Deep Brain Stimulation was overall found to be a promising and safe treatment for Mood and Anxiety Disorders, there are not enough studies proving its efficacy in wide samples and in the presence of more complex variables.
Keywords: Anxiety disorder, deep brain stimulation, depression, obsessive compulsive disorder.
CNS & Neurological Disorders - Drug Targets
Title:Deep Brain Stimulation: A New Treatment in Mood and Anxiety Disorders
Volume: 13 Issue: 6
Author(s): Bruna Velasques, Claudia Diniz, Silmar Teixeira, Consuelo Cartier, Caroline Peressutti, Farmy Silva, Marcele de Carvalho, Aline Novaes, Juliana Bittencourt, Antonio Egidio Nardi, Elie Cheniaux, Luis Basile, Mauricio Cagy, Roberto Piedade and Pedro Ribeiro
Affiliation:
Keywords: Anxiety disorder, deep brain stimulation, depression, obsessive compulsive disorder.
Abstract: This article considered already existing studies about Deep Brain Stimulation in Mood and Anxiety Disorders. In particular, articles regarding Obsessive-Compulsive Disorder and Major Depression were mostly analyzed, due to the lack of researches about other types of Mood and Anxiety Disorders. We have concentrated on the target areas where Deep Brain Stimulation was most commonly applied, and on the effects this measure had on treatment-refractory patients. The obtained results showed that the stimulation of the: nucleus accumbens, subgenual cingulate cortex and ventral capsule/ventral striatum, has a positive influence on the development of the disorders investigated, sometimes showing the complete remission of the symptoms. Although Deep Brain Stimulation was overall found to be a promising and safe treatment for Mood and Anxiety Disorders, there are not enough studies proving its efficacy in wide samples and in the presence of more complex variables.
Export Options
About this article
Cite this article as:
Velasques Bruna, Diniz Claudia, Teixeira Silmar, Cartier Consuelo, Peressutti Caroline, Silva Farmy, Carvalho de Marcele, Novaes Aline, Bittencourt Juliana, Nardi Egidio Antonio, Cheniaux Elie, Basile Luis, Cagy Mauricio, Piedade Roberto and Ribeiro Pedro, Deep Brain Stimulation: A New Treatment in Mood and Anxiety Disorders, CNS & Neurological Disorders - Drug Targets 2014; 13 (6) . https://dx.doi.org/10.2174/1871527313666140612122929
DOI https://dx.doi.org/10.2174/1871527313666140612122929 |
Print ISSN 1871-5273 |
Publisher Name Bentham Science Publisher |
Online ISSN 1996-3181 |
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
Related Articles
-
Bacterial Multidrug Efflux Pumps of the Major Facilitator Superfamily as Targets for Modulation
Infectious Disorders - Drug Targets Structure-Based Rational Design of Adenosine Receptor Ligands
Current Topics in Medicinal Chemistry Adult and Embryonic Stem Cells in Cartilage Repair
Current Rheumatology Reviews Marrow Stromal Cells: Implications in Health and Disease in the Nervous System
Current Molecular Medicine Therapeutic Agents for Alzheimers Disease
Current Medicinal Chemistry - Central Nervous System Agents Clinical and Pharmacological Aspects of Inflammatory Demyelinating Diseases in Childhood: An Update
Current Neuropharmacology Administration of Ethanolic Extract of Ocimum Basilicum Leaves Attenuates Depression like Behavior in the Rats Sensitized by Ovalbumin
Current Nutrition & Food Science Recent Advancements in Fuzzy C-means Based Techniques for Brain MRI Segmentation
Current Medical Imaging Atomoxetine Protects Against NMDA Receptor-mediated Hippocampal Neuronal Death Following Transient Global Cerebral Ischemia
Current Neurovascular Research Recent Advances in the Treatment of Neurogenic Erectile Dysfunction
Recent Patents on CNS Drug Discovery (Discontinued) Parkinson's Disease, Diabetes and Cognitive Impairment
Recent Patents on Endocrine, Metabolic & Immune Drug Discovery (Discontinued) COMMENTARY: Magnetic Resonance Techniques Applied to Parkinson’s Disease
CNS & Neurological Disorders - Drug Targets Newer Approaches to the Discovery of Glitazones
Mini-Reviews in Organic Chemistry Link of COVID-19 and Neurodegenerative Disorders
CNS & Neurological Disorders - Drug Targets MicroRNAs: Modulators of Tooth Development
MicroRNA Mice in Ecstasy: Advanced Animal Models in the Study of MDMA
Current Pharmaceutical Biotechnology Glutamatergic Neurotransmission As Molecular Target of New Anticonvulsants
Current Topics in Medicinal Chemistry Editorial [Hot Topic: From Structural Plasticity to Functional Diversity of 7TMRs: Biased Agonism and Beyond (Executive Guest Editor: Christodoulos S. Flordellis)]
Current Pharmaceutical Design The Endocannabinoid System and Pain
CNS & Neurological Disorders - Drug Targets Disruption of Circadian Rhythms and Sleep in Critical Illness and its Impact on the Development of Delirium
Current Pharmaceutical Design