Mini-Review: Polyamines Metabolism, Toxicity and Potent Therapeutical Use

Lamia      Djouhri-Bouktab; Jean M.      Rolain; Jean M.      Brunel

doi:10.2174/22113525113119990118

Abstract

In recent years, extensive researches have emphasized the fact that polyamines conjugates acting as possessing antitumor, antimicrobial candidates are becoming important in the biogical and medicinal field. In this review, a general design strategy of polyamine conjugates as well as recent progress in both fundamental mechanism studies and potent therapeutic use as anti infectious agents are provided for the readers.

Keywords: Anticancer activity, antimicrobial activity, metabolism, polyamines, therapeutical use.