Abstract
The use of polymers in different fields of modern medicine has generated significant advances in tissue engineering, diagnostic and therapeutic strategies. Polymers have been used to control the rate of drug release, prevent toxicity, protect drugs from degradation before delivery, target drugs to the site of action, improve absorption, bioavailability and therapeutic efficacy. Although synthetic polymers allow producing tailor-made materials, however natural polymers exhibit the advantages of excellent biodegradability, biocompatibility, cost-effectiveness and environmental friendliness. This review presents the current status of research and clinical applications of natural polymers as drug delivery systems for different administration routes.
Keywords: Natural polymers, proteins, polysaccharides, drug delivery, mucosal delivery, enteral delivery, central nervous system delivery.
Current Organic Chemistry
Title:Biomedical Applications of Natural Polymers for Drug Delivery
Volume: 18 Issue: 2
Author(s): Mariana Carmen Chifiriuc, Alexandru Mihai Grumezescu, Valentina Grumezescu, Eugenia Bezirtzoglou, Veronica Lazar and Alexandra Bolocan
Affiliation:
Keywords: Natural polymers, proteins, polysaccharides, drug delivery, mucosal delivery, enteral delivery, central nervous system delivery.
Abstract: The use of polymers in different fields of modern medicine has generated significant advances in tissue engineering, diagnostic and therapeutic strategies. Polymers have been used to control the rate of drug release, prevent toxicity, protect drugs from degradation before delivery, target drugs to the site of action, improve absorption, bioavailability and therapeutic efficacy. Although synthetic polymers allow producing tailor-made materials, however natural polymers exhibit the advantages of excellent biodegradability, biocompatibility, cost-effectiveness and environmental friendliness. This review presents the current status of research and clinical applications of natural polymers as drug delivery systems for different administration routes.
Export Options
About this article
Cite this article as:
Chifiriuc Carmen Mariana, Grumezescu Mihai Alexandru, Grumezescu Valentina, Bezirtzoglou Eugenia, Lazar Veronica and Bolocan Alexandra, Biomedical Applications of Natural Polymers for Drug Delivery, Current Organic Chemistry 2014; 18 (2) . https://dx.doi.org/10.2174/138527281802140129104525
DOI https://dx.doi.org/10.2174/138527281802140129104525 |
Print ISSN 1385-2728 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5348 |
Call for Papers in Thematic Issues
Catalytic C-H bond activation as a tool for functionalization of heterocycles
The major topic is the functionalization of heterocycles through catalyzed C-H bond activation. The strategies based on C-H activation not only provide straightforward formation of C-C or C-X bonds but, more importantly, allow for the avoidance of pre-functionalization of one or two of the cross-coupling partners. The beneficial impact of ...read more
Related Journals
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
- Announcements
Related Articles
-
Cancer Drug Discovery Targeting Histone Methyltransferases: An Update
Current Medicinal Chemistry Editorial [Hot topic: QSAR and Complex Networks in Pharmaceutical Design, Microbiology, Parasitology, Toxicology, Cancer and Neurosciences (Executive Editor: Humberto Gonzalez-Diaz)]
Current Pharmaceutical Design Dual Cyclooxygenase and Carbonic Anhydrase Inhibition by Nonsteroidal Anti-Inflammatory Drugs for the Treatment of Cancer
Current Medicinal Chemistry Fluorescent Porphyrin with an Increased Uptake in Peripheral Blood Cell Subpopulations from Colon Cancer Patients
Medicinal Chemistry Natural Products as Anticancer Agents
Current Drug Targets Identification of Novel Drug Targets for Angiostatic Cancer Therapy; It Takes Two to Tango
Current Pharmaceutical Design Expression of Cytochrome P450 in Lung Tumor
Current Drug Metabolism Functionalized Upconversion Nanoparticles: Versatile Nanoplatforms for Translational Research
Current Molecular Medicine Targeted Drug Delivery System for Platinum-based Anticancer Drugs
Mini-Reviews in Medicinal Chemistry Multiple Functions of Generic Drugs: Future Perspectives of Aureolic Acid Group of Anti-Cancer Antibiotics and Non-Steroidal Anti-Inflammatory Drugs
Mini-Reviews in Medicinal Chemistry The Role of STAT3 Signaling in Mediating Tumor Resistance to Cancer Therapy
Current Drug Targets The Effects of Insulin and Insulin-Like Growth Factors on Tumor Vascularization: New Insights of Insulin-Like Growth Factor Family in Cancer
Current Medicinal Chemistry Liposomes as Versatile Platform for Cancer Theranostics: Therapy, Bio-imaging, and Toxicological Aspects
Current Pharmaceutical Design The Clinical Perspective on Value of 3D, Thin Slice T2-Weighted Images in 3T Pelvic MRI for Tumors
Current Medical Imaging Review: Recent Clinical Trials in Epigenetic Therapy
Reviews on Recent Clinical Trials Repulsive Guidance Molecules (RGMs) and Their Potential Implication in Cancer as Co-receptor of BMPs
Current Signal Transduction Therapy Vitamin D Supplementation and Cancer: Review of Randomized Controlled Trials
Anti-Cancer Agents in Medicinal Chemistry The Role of Protein Kinase C-alpha (PKC-α) in Cancer and its Modulation by the Novel PKC-α-Specific Inhibitor Aprinocarsen
Current Pharmaceutical Design Up-Regulation of MBD1 Promotes Pancreatic Cancer Cell Epithelial-Mesenchymal Transition and Invasion by Epigenetic Down-Regulation of E-Cadherin
Current Molecular Medicine Editorial:[Special Issue: Post-Translational Proteomics and its Application (Guest Editor: Qing-Yu He)]
Current Proteomics