Abstract
Glyconanoparticles are the subject of numerous literatures and are emerging for applications in biomedicine, glycoscience, and material science due to their unique properties. They are hybrid materials each of which contains a nanoparticle core surrounded by a carbohydrate shell. The core can be metallic, magnetic, and/or photoluminescent, while the shell may be composed of mono-, di-, oligo- and/or poly-saccharides. Sugars are attached to the surface of the nanoparticles through covalent or non-covalent interaction. Here, we give a brief summary of the synthetic methodologies adopted in the preparation of different types of glyconanoparticles, which can be utilized in various applications including catalysis, drug delivery, vaccine, imaging and study of carbohydrate-lectin interactions.
Keywords: Glyconanoparticles, methodologies, carbohydrate-lectin interactions, biomedicine.
Graphical Abstract
Current Organic Chemistry
Title:Synthesis and Applications of Glyconanoparticles
Volume: 20 Issue: 14
Author(s): Baoyong Liu, Xiaowei Lu, Hong Ruan, Jiwei Cui and Hongguang Li
Affiliation:
Keywords: Glyconanoparticles, methodologies, carbohydrate-lectin interactions, biomedicine.
Abstract: Glyconanoparticles are the subject of numerous literatures and are emerging for applications in biomedicine, glycoscience, and material science due to their unique properties. They are hybrid materials each of which contains a nanoparticle core surrounded by a carbohydrate shell. The core can be metallic, magnetic, and/or photoluminescent, while the shell may be composed of mono-, di-, oligo- and/or poly-saccharides. Sugars are attached to the surface of the nanoparticles through covalent or non-covalent interaction. Here, we give a brief summary of the synthetic methodologies adopted in the preparation of different types of glyconanoparticles, which can be utilized in various applications including catalysis, drug delivery, vaccine, imaging and study of carbohydrate-lectin interactions.
Export Options
About this article
Cite this article as:
Liu Baoyong, Lu Xiaowei, Ruan Hong, Cui Jiwei and Li Hongguang, Synthesis and Applications of Glyconanoparticles, Current Organic Chemistry 2016; 20 (14) . https://dx.doi.org/10.2174/1385272820666151207194453
DOI https://dx.doi.org/10.2174/1385272820666151207194453 |
Print ISSN 1385-2728 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5348 |
Call for Papers in Thematic Issues
Catalytic C-H bond activation as a tool for functionalization of heterocycles
The major topic is the functionalization of heterocycles through catalyzed C-H bond activation. The strategies based on C-H activation not only provide straightforward formation of C-C or C-X bonds but, more importantly, allow for the avoidance of pre-functionalization of one or two of the cross-coupling partners. The beneficial impact of ...read more
Chemistry and Biology of Carbohydrates
Carbohydrates are one of the most abundant natural products and are considered to be extremely important biomolecules for their ever-increasing impact on chemistry and biology. Their role in several important biological processes, notably energy storage, transport, modulation of protein function, intercellular adhesion, malignant transformation, signal transduction, viral, and bacterial cell ...read more
Related Journals
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
- Announcements
Related Articles
-
Recent Advances in Minimal Access Surgery for Infants and Children
Current Pediatric Reviews Template Synthesis of Tubular Nanostructures for Loading Biologically Active Molecules
Current Topics in Medicinal Chemistry Microbial Antigenic Pressure and Evolution of the Immune Response: Toward a Better Understanding of the Human Immune System in Health and Disease and Therapeutic Interventions
Endocrine, Metabolic & Immune Disorders - Drug Targets The Pharmacogenomics “Side-effect” of TP53/EGFR in Non-small Cell Lung Cancer Accompanied with Atorvastatin Therapy: A Functional Network Analysis
Anti-Cancer Agents in Medicinal Chemistry Monoclonal Antibodies: A Prospective and Retrospective View
Current Medicinal Chemistry Assessing Activation States in Microglia
CNS & Neurological Disorders - Drug Targets Nanoradiopharmaceuticals for Nanomedicine: Building the Future
Recent Patents on Nanomedicine Neuropeptides as Autocrine Growth Factors in Cancer Cells
Current Pharmaceutical Design The Reciprocal Interaction: Chemotherapy and Tumor Microenvironment
Current Drug Discovery Technologies Cell Surface Nucleolin as a Target for Anti-Cancer Therapies
Recent Patents on Anti-Cancer Drug Discovery Neuronal and Extraneuronal Nicotinic Acetylcholine Receptors
Current Neuropharmacology Anti-cancer Drug Delivery Using Metal Organic Frameworks (MOFs)
Current Medicinal Chemistry dUTPase in Human Neoplastic Cells as a Potential Target for Therapeutic Intervention
Current Protein & Peptide Science Recent Developments in the Formulation of Nanoliposomal Delivery Systems
Current Nanomaterials Preparation and Evaluation of in vitro Self-assembling HSA Nanoparticles for Cabazitaxel
Anti-Cancer Agents in Medicinal Chemistry Targeting the Nuclear Transport Machinery by Rational Drug Design
Current Pharmaceutical Design Identification of Novel Key Targets and Candidate Drugs in Oral Squamous Cell Carcinoma
Current Bioinformatics A Simplified Protocol Employing Elacridar in Rodents: A Screening Model in Drug Discovery to Assess P-gp Mediated Efflux at the Blood Brain Barrier
Drug Metabolism Letters Sirtuin3 in Neurological Disorders
Current Drug Research Reviews Recombinant Interleukin-12 for Immunotherapy: A Double-Sided Sword
Current Medicinal Chemistry - Immunology, Endocrine & Metabolic Agents