Polymeric Materials and Formulation Technologies for Modified-Release Tablet Development

J.      Zarate; M.      Igartua; R.   M.   Hernandez; J.   L.   Pedraz

doi:10.2174/138955709790361539

Abstract

Over the last years significant advances have been made in the area of drug delivery with the development of modified-release (MR) dosage forms. The present review is divided into two parts, one dealing with technologies for the design of modified-release drug delivery tablets and the other with the use of synthetic and natural polymers that are capable of controlling drug release.

Keywords: Matrix tablets, modified-release, controlled-release, extended-release, multilayer, coating, zero-order, natural polymers