Abstract
Intravenous thrombolysis with rt-PA within three hours of symptom onset is the only proven effective treatment for acute ischemic stroke. The European license limits the use of rt-PA to patients aged < 80 years for the lack of clear evidence of safety and efficacy of this treatment in the elderly.
Keywords: Ischemic stroke, Intravenous thrombolysis, rt-PA, Elderly
Letters in Drug Design & Discovery
Title: Intravenous Thrombolysis with rt-PA in Acute Stroke Patients Aged ≥80 Years
Volume: 5 Issue: 3
Author(s): S. Lorenzano, F. Orzi, E. Puca and D. Toni
Affiliation:
Keywords: Ischemic stroke, Intravenous thrombolysis, rt-PA, Elderly
Abstract: Intravenous thrombolysis with rt-PA within three hours of symptom onset is the only proven effective treatment for acute ischemic stroke. The European license limits the use of rt-PA to patients aged < 80 years for the lack of clear evidence of safety and efficacy of this treatment in the elderly.
Export Options
About this article
Cite this article as:
Lorenzano S., Orzi F., Puca E. and Toni D., Intravenous Thrombolysis with rt-PA in Acute Stroke Patients Aged ≥80 Years, Letters in Drug Design & Discovery 2008; 5 (3) . https://dx.doi.org/10.2174/157018008784084009
DOI https://dx.doi.org/10.2174/157018008784084009 |
Print ISSN 1570-1808 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-628X |
Related Journals
Related Books
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
Related Articles
-
Therapeutic Potential of N-Acetylcysteine for Wound Healing, Acute Bronchiolitis, and Congenital Heart Defects
Current Drug Metabolism Editorial (Thematic Issue: Mitochondrial and Metabolism: Novel Targets for Heart Failure)
Current Pharmaceutical Design An Overview of Olive Oil Biomolecules
Current Biotechnology Clinical and Molecular Genetic Aspects of Hypertrophic Cardiomyopathy
Current Cardiology Reviews Characterization of Adipose-Derived Stem Cells: An Update
Current Stem Cell Research & Therapy Role of Oxidative-Nitrosative Stress and Downstream Pathways in Various Forms of Cardiomyopathy and Heart Failure
Current Vascular Pharmacology Barriers to Optimising Prescribing and Deprescribing in Older Adults with Dementia: A Narrative Review
Current Clinical Pharmacology Inhibition of Tumor Angiogenesis by Antibodies, Synthetic Small Molecules and Natural Products
Current Medicinal Chemistry Ethical and Policy Considerations in the Application of Pharmacogenomic Testing for Tardive Dyskinesia: Case Study of the Dopamine D3 Receptor
Current Pharmacogenomics and Personalized Medicine Long Noncoding RNA OIP5-AS1 Overexpression Promotes Viability and Inhibits High Glucose-Induced Oxidative Stress of Cardiomyocytes by Targeting MicroRNA-34a/SIRT1 Axis in Diabetic Cardiomyopathy
Endocrine, Metabolic & Immune Disorders - Drug Targets Omega-3 Fatty Acids: Role in Metabolism and Cardiovascular Disease
Current Pharmaceutical Design New Developments in Anti-Platelet Therapies Potential Use of CD39/Vascular ATP Diphosphohydrolase in Thrombotic Disorders
Current Drug Targets Lycopene Modulation of Molecular Targets Affected by Smoking Exposure
Current Cancer Drug Targets Functional Polymeric Nano/Microparticles for Surface Adsorption and Delivery of Protein and DNA Vaccines
Current Drug Delivery Nutlin-3, A p53-Mdm2 Antagonist for Nasopharyngeal Carcinoma Treatment
Mini-Reviews in Medicinal Chemistry Serpin Regulation of Fibrinolytic System: Implications for Therapeutic Applications in Cardiovascular Diseases
Cardiovascular & Hematological Agents in Medicinal Chemistry Cytochrome P450 and the Biological Clock in Mammals
Current Drug Metabolism The Endothelium and Platelets in Cardiovascular Disease: Potential Targets for Therapeutic Intervention
Current Medicinal Chemistry - Cardiovascular & Hematological Agents Treating Hypertension in the Elderly: Common Problems and Solutions
Current Hypertension Reviews An Overview of Innovations in Analysis and Beneficial Health Effects of Wine Polyphenols
Mini-Reviews in Medicinal Chemistry