Abstract
Quinoline derivatives constitute an important class of compounds for new drug development. As a large number of experimental and theoretical studies have shown that the quinoline ring system is an important structural unit widely existing in alkaloids, therapeutics and synthetic analogues with exciting biological activities. The present review provides recent antioxidant activities covering in vivo and in vitro studies of natural and synthetic analogues, as well as the proposed mechanisms of action and structure-activity relationships.
Keywords: Antioxidant activity, free radical, quinoline, oxidative stress
Mini-Reviews in Medicinal Chemistry
Title:Recent Studies of Antioxidant Quinoline Derivatives
Volume: 13 Issue: 3
Author(s): M. Orhan Puskullu, Betul Tekiner and Sibel Suzen
Affiliation:
Keywords: Antioxidant activity, free radical, quinoline, oxidative stress
Abstract: Quinoline derivatives constitute an important class of compounds for new drug development. As a large number of experimental and theoretical studies have shown that the quinoline ring system is an important structural unit widely existing in alkaloids, therapeutics and synthetic analogues with exciting biological activities. The present review provides recent antioxidant activities covering in vivo and in vitro studies of natural and synthetic analogues, as well as the proposed mechanisms of action and structure-activity relationships.
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Cite this article as:
Orhan Puskullu M., Tekiner Betul and Suzen Sibel, Recent Studies of Antioxidant Quinoline Derivatives, Mini-Reviews in Medicinal Chemistry 2013; 13 (3) . https://dx.doi.org/10.2174/1389557511313030005
DOI https://dx.doi.org/10.2174/1389557511313030005 |
Print ISSN 1389-5575 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5607 |
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