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当代肿瘤药物靶点

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ISSN (Print): 1568-0096
ISSN (Online): 1873-5576

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Research Article

经动脉化疗栓塞联合微波消融与单用微波治疗中型肝细胞癌

卷 22, 期 1, 2022

发表于: 20 January, 2022

页: [77 - 85] 页: 9

弟呕挨: 10.2174/1568009622666220117094146

价格: $65

摘要

背景与目的：肝细胞癌 (HCC) 是第五大常见癌症，也是癌症相关死亡的第二大原因。 HCC 和肝硬化的唯一确定性治疗方法是肝移植，但在某些地区等待时间长且供体器官数量相对固定会对肝移植的可及性产生负面影响。这项工作的目的是评估和比较单独接受经皮微波消融 (MWA) 和联合 TACE 的中型 HCC 患者的短期结果。 方法：本前瞻性研究纳入 40 例中型 HCC 病灶患者，分为两组； A 组包括 20 名患者接受 TACE 治疗，然后在 2 周后经皮 MWA 治疗，B 组包括 20 名患者接受 2 次经皮 MWA 治疗，间隔 2 周。从两组获得完整的病史采集、临床检查、实验室检查、腹部超声检查和腹部三相计算机断层扫描 (CT) 造影。在治疗后1个月和3个月对病例进行实验室和放射学随访。 结果：在开始治疗前，两个研究组的病例在社会人口学标准、实验室测量和临床标准方面没有统计学上的显着差异。联合治疗组的反应略好，但没有显示出统计学上的显着差异。 MWA组并发症发生率较高。 结论：肝细胞癌是HCV相关肝硬化的常见并发症。 TACE-MWA 的联合导致比 MWA 更好的反应率和更少的并发症。

关键词: 微波消融，经动脉化疗栓塞，肝细胞癌，死亡率，并发症，复发

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