Abstract
Coronavirus disease 2019 (SARS-CoV-2) (COVID-19) has recently raised worldwide public health concerns. The available data on COVID-19 in patients with diabetes is limited but generally indicate that there is an increased risk of developing COVID-19 infection in diabetic patients, which ultimately impacts the overall patient’s survival. Various aspects might be involved; however, the exact mechanisms and interrelationships between diabetes and the novel COVID-19 have not yet been fully elucidated. This review summarizes the possible mechanisms by which present diabetes predispose individuals to COVID-19 infection, modulates the hostviral interactions and increases the risk of mortality. We hope this review can provide beneficial information for further studies and contribute to improved disease management of diabetic patients with COVID-19.
Keywords: Diabetes, COVID-19, mechanism, risk factor, prognosis, review, SARS-CoV-2.
Current Pharmaceutical Design
Title:Diabetes and COVID-19; a Review of Possible Mechanisms
Volume: 27 Issue: 21
Author(s): Reyhaneh Moradi-Marjaneh, Fereshteh Asgharzadeh, Elnaz Khordad and Mahdi Moradi Marjaneh*
Affiliation:
- Department of Infectious Disease, Faculty of Medicine, Imperial College London, London,United Kingdom
Keywords: Diabetes, COVID-19, mechanism, risk factor, prognosis, review, SARS-CoV-2.
Abstract: Coronavirus disease 2019 (SARS-CoV-2) (COVID-19) has recently raised worldwide public health concerns. The available data on COVID-19 in patients with diabetes is limited but generally indicate that there is an increased risk of developing COVID-19 infection in diabetic patients, which ultimately impacts the overall patient’s survival. Various aspects might be involved; however, the exact mechanisms and interrelationships between diabetes and the novel COVID-19 have not yet been fully elucidated. This review summarizes the possible mechanisms by which present diabetes predispose individuals to COVID-19 infection, modulates the hostviral interactions and increases the risk of mortality. We hope this review can provide beneficial information for further studies and contribute to improved disease management of diabetic patients with COVID-19.
Export Options
About this article
Cite this article as:
Moradi-Marjaneh Reyhaneh , Asgharzadeh Fereshteh , Khordad Elnaz and Marjaneh Moradi Mahdi *, Diabetes and COVID-19; a Review of Possible Mechanisms, Current Pharmaceutical Design 2021; 27 (21) . https://dx.doi.org/10.2174/1381612827666210303141846
DOI https://dx.doi.org/10.2174/1381612827666210303141846 |
Print ISSN 1381-6128 |
Publisher Name Bentham Science Publisher |
Online ISSN 1873-4286 |
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
- Announcements
Related Articles
-
Phytochemical Informatics and Virtual Screening of Herbs Used in Chinese Medicine
Current Pharmaceutical Design Alpha-MSH Targeted Liposomal Nanoparticle for Imaging in Inflammatory Bowel Disease (IBD)
Current Pharmaceutical Design The Immunomodulatory Effects of Physical Activity
Current Pharmaceutical Design Rapid Response Research - SARS Coronavirus Vaccines and Application of Processes to Other Emerging Infectious Diseases
Current Immunology Reviews (Discontinued) A Short Review on Important Drugs Under Clinical Trial Against COVID-19
Mini-Reviews in Medicinal Chemistry <i>In Silico</i> Prediction and Designing of Potential siRNAs to be used as Antivirals Against SARS-CoV-2
Current Pharmaceutical Design Covid-19: An Update on Clinical Features, Diagnosis, and Treatment Strategies
Coronaviruses Potential Drug Options for Treatment of COVID-19: A Review
Coronaviruses Symptoms, Transmission, Prevention and Treatment of Pandemic Corona Virus: A Review
Coronaviruses Pathogenesis, Clinical Manifestation, Diagnosis, Pathological Findings, Treatment Options, Preventive Measures, and Risk Factors of COVID-19
Coronaviruses Production, Novel Assay Development and Clinical Applications of Monoclonal Antibodies
Recent Patents on Anti-Cancer Drug Discovery Severe Community-Acquired Pneumonia (CAP) due to Atypical Pathogens
Current Respiratory Medicine Reviews Clinical Characteristics of Inpatients with Coronavirus Disease 2019 and Acute Ischemic Stroke: From Epidemiology to Outcomes
Current Neurovascular Research The Role of CO-RADS Scoring System in the Diagnosis of COVID-19 Infection and its Correlation with Clinical Signs
Current Medical Imaging Transmissibility and Epidemicity of COVID-19 in India: A Case Study
Recent Advances in Anti-Infective Drug Discovery Misinformation About COVID-19 and Confidential Information Leakage: Impacts on the Psychological Well-being of Indians
Current Psychiatry Research and Reviews Current Strategies for Probing Substrate Specificity of Proteases
Current Medicinal Chemistry COVID-19 and Renal Diseases: An Update
Current Drug Targets Azithromycin Use in COVID-19 Patients: Implications on the Antimicrobial Resistance
Current Topics in Medicinal Chemistry Stem Cell Therapy: A Promising Approach in Treatment of COVID-19
Current Stem Cell Research & Therapy